Melanoblasts as Multipotent Cells in Murine Skin

Melanoblasts are melanocyte precursors that are derived from neural crest cells (NCCs). Recently we showed that melanoblasts differentiate into not only pigmented melanocytes but also into other NCCs derivatives. Here, we describe methods for the isolation of melanoblasts from mouse skin by flow-cytometry. Methods for culturing the isolated melanoblasts, allowing them to express their multipotentiality, are also described.