Genetic Analysis of Cystic Fibrosis Airway Epithelial Cells

More than 500 different mutations have been described to date on the cystic fibrosis (CF) gene (1 ). The most frequent mutation is the so-called ΔF508 mutation, which accounts for 30–50%;of CF chromosomes in southern European countries and for 50–80%; of CF chromosomes in the United States, Canada, Argentina, and central and northern European countries