Preparation of Retroviral Vectors for Cell-Cycle-Targeted Gene Therapy of Lung Cancer

Lung cancer is one of the leading causes of cancer death in the world (1 ). The high mortality rate for lung cancer may be due to either or both the absence of standard clinical procedures for early diagnosis of tumors compared to breast, prostate, and colon cancers, and lack of effective treatments in more advanced stages of the disease (2 ).