Somatic Cell Knockouts of Tumor Suppressor Genes
Gene targeting is the modification of specific DNA sequences in a living organis
Gene targeting is the modification of specific DNA sequences in a living organism. Three requirements must be met in order for gene targeting to be successful (1 ). The process must be directed, so that it affects only the locus of choice. The targeting procedure requires specificity, such that a predetermined sequence can be inserted or substituted at the target locus. Finally, the process should be efficient.
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Clonality Analysis by T-Cell Receptor PCR and High-Resolution Electrophoresis in the Diagnosis of Cu
During T-cell maturation, T-cell receptor (TCR) gene segment...
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Immunocytochemical Detection and Characterisation of Individual Micrometastatic Tumour Cells
Detection of micrometastases in the bone marrow (BM) of canc...