Neuroepithelial Differentiation Induced by ECM Molecules
Many important processes in the development of the vertebrate central nervous sy
Many important processes in the development of the vertebrate central nervous system (CNS) rely on signals induced by extracellular matrix (ECM) components (1 ,2 ). These molecules are known to contain multiple functional domains that deliver distinct signals to the cells with which they interact. We will focus here on a well-known ECM glycoprotein, laminin-1, which plays a variety of roles in the development of the CNS (2 ).
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Cell-Based Methods for the Identification of MYC-Inhibitory Small Molecules
Oncoproteins encoded by dominant oncogenes have long been co...
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Real-Time Visualization and Quantification of Native Ras Activation in Single Living Cells
Members of the Ras family of small guanosine triphosphate ph...