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细胞技术

Promoter Methylation in Head and Neck Tumorigenesis

2025-03-14 细胞技术 加入收藏
In addition to genetic alterations of gains and losses, epigenetic events of pro

In addition to genetic alterations of gains and losses, epigenetic events of promoter methylation appear to further undermine a destabilized genomic repertoire in squamous head and neck carcinoma (HNSCC). This chapter provides an overview of frequently methylated tumor suppressor genes in benign head and neck papillomas, primary HNSCC tumors, and HNSCC cell lines and their relevance as epigenetic markers in head and neck tumorigenesis.

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