Comparative Genomic Hybridization
Comparative genomic hybridization (CGH ) allows a genome-wide survey of the rela
Comparative genomic hybridization (CGH ) allows a genome-wide survey of the relative copy number of tumor DNA in a single hybridization. The tumor-cell DNA (Test DNA) is hybridized together with a sex-matched normal DNA (Reference DNA) onto normal metaphase spreads. Test DNA and Reference DNA are labeled with fluorochrome-conjugated reagents of different color, thereby allowing the detection of genetic imbalance in the abnormal cells.
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Breast Cancer Proteomics Using Two-Dimensional Electrophoresis: Studying the Breast Cancer Proteome
Proteomics has emerged as a powerful approach for studying d...
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Prediction of the Biological Effect of Polymorphisms Within MicroRNA Binding Sites
MicroRNAs (miRNAs) are negative gene regulators acting at th...