Molecular Characterization of Melanoma-Derived Antigens
In the last decade, many antigens expressed by tumors and recognized by the immune system have been identified. Melanoma was among the first tumors found to express such tumor-associated antigens, and, therefore, melanoma is currently one of the best and extensively studied tumors for which new techniques have been introduced to optimize the characterization of tumor antigens. In this chapter, we discuss the techniques used for identification of melanoma-expressed antigens recognized by cytotoxic T-lymphocytes (CTLs). In more detail, we describe in Subheading 3. the reverse immunology method.
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Chemosensitization of Tumor Cells: Inactivation of Nuclear Factor-Kappa B Associated with Chemosensi
Combination chemotherapy has been shown to be more effective...
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Clinical Development of Antisense Oligonucleotides as Anti-Cancer Therapeutics
Antisense oligonucleotides (AONs) are one of the several typ...