CD33分子

CD33 分子   CD33 常用单克隆抗体或代号： MY9,H153,L4F3 主要表达细胞： My,BM [M] 分子质量(kDa)和结构： gp67(IgSF) 功    能： 参与造血   CD33 Myeloid cell antigen (also CD13); a sialoadhesin that may mediate cell-to-cell adhesion, acts as a receptor that inhibits the proliferation of normal and leukemic myeloid cells Positive staining (normal): Precursor myeloid cells; most monocytic cells, epidermal Langerhans cells (variable) Positive staining (disease): AML M1-M5 (75-85%), M7 (variable), CML (90%); blasts (all), some ALL Negative staining: granulocytes, mature bone marrow cells, non-myeloid cells