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General Design and Construction of RNase P Ribozymes for Gene-Targeting Applications
RNase P ribozyme, such as M1 RNA, the catalytic RNA subunit of RNase P from Esch
2025-03-27 82 -
Genome Wide Full-Length Transcript Analysis Using 5 and 3 Paired-End-Tag Next Generation Sequencing
RNA-PET is a paired end tag (PET) sequencing method for full-length mRNA transcr
2025-03-27 71 -
Probing the Mechanics of the Complete DNA Transcription Cycle in Real-Time Using Optical Tweezers
RNA polymerase (RNAP) is a DNA-dependent motor protein that links ribonucleotide
2025-03-27 76 -
A rapid and sensitive assay for quantification of siRNA efficiency and specificity
RNA Interference has rapidly emerged as an efficient procedure for knocking down
2025-03-27 100 -
Quantification of siRNAs In Vitro and In Vivo
RNA interference (RNAi) is a regulatory mechanism of eukaryotic cells that uses
2025-03-27 91 -
Nonradioactive Methods for the Detection of RNA-Protein Interaction
RNA in biological systems is associated with proteins. Recent work in eukaryotes
2025-03-27 74 -
Preparation of RNA Gel Blots
RNA gel blots (often referred to as Northern gel blots) are frequently used in t
2025-03-27 83 -
Preparation of RNA Dot Blots
RNA dot hybridizations were first described by Kafatos et al. (1 ). These hybrid
2025-03-27 64 -
Quantitation of Ribozyme Target Abundance by QCPCR
Ribozymes show promise as therapeutic agents for the downregulation of specific
2025-03-27 75 -
Computer-Aided Calculation of the Local Folding Potential of Target RNA and Its Use for Ribozyme Des
Ribozymes first bind their target via complementary sequences like a conventiona
2025-03-27 81 -
Maxizyme Technology
Ribozymes are small and versatile nucleic acids that can cleave RNAs at specific
2025-03-27 82 -
Ligation of RNA Molecules by the Hairpin Ribozyme
Ribozymes are capable of catalyzing a variety of RNA cleavage, ligation, and spl
2025-03-27 87 -
Crystallographic Analysis of Small Ribozymes and Riboswitches
Ribozymes and riboswitches are RNA motifs that accelerate biological reactions a
2025-03-27 67 -
Ribozyme as an approach for growth suppression of human pancreatic cancer
Ribozymes (catalytic RNAs, RNA enzymes) are effective modulators of gene express
2025-03-27 86 -
Assay for Evaluating Ribonuclease H-Mediated Degradation of RNA-Antisense Oligonucleotide Duplexes
Ribonucleases H are complex enzymes whose functions are not clearly understood,
2025-03-27 71
