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  • Regulatory Aspects for Translating Gene Therapy Research into the Clinic

    Regulatory Aspects for Translating Gene Therapy Research into the Clinic

    Gene therapy products are highly regulated, therefore moving a promising candida

    2025-03-18 35
  • 99mTc-Annexin A5 Uptake and Imaging to Monitor Chemosensitivity

    99mTc-Annexin A5 Uptake and Imaging to Monitor Chemosensitivity

    Most anticancer agents act by inducing apoptosis in sensitive tumor cells. Hence

    2025-03-18 38
  • Microsatellite Analysis of the Insulin-Like Growth Factor II Receptor in Colorectal Carcinomas

    Microsatellite Analysis of the Insulin-Like Growth Factor II Receptor in Colorectal Carcinomas

    The insulin-like growth factor II (IGFII) growth control pathway is comprised of

    2025-03-18 34
  • Frozen Biopsy Collection and Storage: Frozen Biopsy Samples

    Frozen Biopsy Collection and Storage: Frozen Biopsy Samples

    This chapter describes some simple standard operating procedures for the regular

    2025-03-18 39
  • Chromosomal Copy Number Analysis in Melanoma Diagnostics

    Chromosomal Copy Number Analysis in Melanoma Diagnostics

    The majority of melanocytic neoplasms can be correctly diagnosed using routine h

    2025-03-18 36
  • Rocking Adhesion Assay System to Study Adhesion and Transendothelial Migration of Cancer Cells

    Rocking Adhesion Assay System to Study Adhesion and Transendothelial Migration of Cancer Cells

    Adhesion of metastatic cancer cells to the vascular endothelium of the target or

    2025-03-18 37
  • DNA Methylation Changes in Prostate Cancer

    DNA Methylation Changes in Prostate Cancer

    Epigenetic alterations contribute significantly to the development and progressi

    2025-03-18 32
  • Detection of MicroRNAs in Cultured Cells and Paraffin-Embedded Tissue Specimens by In Situ Hybridiza

    Detection of MicroRNAs in Cultured Cells and Paraffin-Embedded Tissue Specimens by In Situ Hybridiza

    Determination of gene expression is essential for understanding the role of a gi

    2025-03-18 39
  • 2-DE-Based Proteomics for the Analysis of Metastasis-Associated Proteins

    2-DE-Based Proteomics for the Analysis of Metastasis-Associated Proteins

    Two-dimensional electrophoresis (2-DE) is a high-resolution technique for analys

    2025-03-18 33
  • Targeting the Mitochondria to Enhance Tumor Suppression

    Targeting the Mitochondria to Enhance Tumor Suppression

    A continuous supply of biochemical energy is required in order for cells to perf

    2025-03-18 44
  • High-Throughput Technology: Green Fluorescent Protein to Monitor Cell Death

    High-Throughput Technology: Green Fluorescent Protein to Monitor Cell Death

    Reliable assessment of cell death is now pivotal to many research programs aimin

    2025-03-18 45
  • A High-Throughput Methodology for Identifying Molecular Targets Overexpressed in Lung Cancers

    A High-Throughput Methodology for Identifying Molecular Targets Overexpressed in Lung Cancers

    As discussed in previous chapters, lung cancer is one of most deadly diseases an

    2025-03-18 41
  • Assessment of Insulin-Like Growth Factors and Mutagen Sensitivity as Predictors of Lung Cancer Risk

    Assessment of Insulin-Like Growth Factors and Mutagen Sensitivity as Predictors of Lung Cancer Risk

    Insulin-like growth factors (IGFs) are mitogenic peptide hormones involved in th

    2025-03-18 40
  • Some Difficult Choices in Cytogenetics

    Some Difficult Choices in Cytogenetics

    It is rare for a full-fledged malignancy cytogenetics service to be started as a

    2025-03-18 39
  • Analysis of the Potential for Pancreatic Cancer Metastasis In Vitro and In Vivo

    Analysis of the Potential for Pancreatic Cancer Metastasis In Vitro and In Vivo

    Pancreatic cancer remains a challenging disease, with an overall 5-year survival

    2025-03-18 40