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Quantitative, Fluorescence-Based In-Situ Assessment of Protein Expression
As companion diagnostics grow in prevalence and importance, the need for accurat
2025-03-15 44 -
Detection of TNF and TNF Receptor mRNA in Cells and Tissues
We describe a semiquantitative reverse transcriptase polymerase chain reaction (
2025-03-15 41 -
Manual Microdissection
The new opportunities of modern assays of molecular biology can only be exploite
2025-03-15 40 -
Measurements of Phospholipases A2, C, and D (PLA2, PLC, and PLD): In Vitro Microassays, Analysis of
In order to be properly divisible, the cell membrane has to be remodeled and int
2025-03-15 42 -
Simultaneous Flow Cytometric Detection of DNA and Cellular Protein Molecules
Flow cytometry (FCM) is a sophisticated technique for rapid simultaneous analysi
2025-03-15 45 -
Zebrafish as a Model for Pancreatic Cancer Research
Elucidation of basic mechanisms that regulate pancreatic organogenesis may help
2025-03-15 35 -
Development of a Scoring System to Screen for BRCA1/2 Mutations
Selection for genetic testing for pathogenic mutations in BRCA1 and BRCA2 is an
2025-03-15 46 -
Primary Mouse Endothelial Cell Culture for Assays of Angiogenesis
The growth of new blood vessels, known as angiogenesis, is a dynamic but highly
2025-03-15 41 -
Methods for Chemoprotection and Chemosensitization: MDR-1 For Chemoprotection Using Retroviruses to
Surgery, radiation therapy, and chemotherapy have been applied to the curative t
2025-03-15 42 -
Fluorescence In Situ Hybridization and Comparative Genomic Hybridization
This chapter discusses the complementary methodologies of fluorescence in situ h
2025-03-15 38 -
Ethics of Cancer Gene Transfer Clinical Research
Cancer gene transfer is a relatively novel intervention strategy. In part becaus
2025-03-15 39 -
Lung-Specific Expression of Mutant p53 as Mouse Model for Lung Cancer
The p53 tumor suppressor gene is the most commonly mutated gene in cancer (1 ,2)
2025-03-15 45 -
Metabolomics of Cancer
Metabolomics, one of the “omic” sciences in systems biology, is the global asses
2025-03-15 39 -
Classification of AML by DNA-Oligonucleotide Microarrays
Accurate diagnosis and classification of leukemias are the bases for the appropr
2025-03-15 39 -
Determining Mutational Status of Immunoglobulin V Genes in Chronic Lymphocytic Leukemia: A Useful Pr
Determining the clonal origins of malignant B-cells will have an impact on disea
2025-03-15 38
