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Epigenetics in Ovarian Cancer
Ovarian cancer is the most lethal gynecological cancer. Due to few early symptom
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Use of DNA Fingerprinting to Detect Genetic Rearrangements in Human Cancer
The polymerase chain reaction (PCR) has revolutionized the isolation and analysi
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Analyzing the Function of Tumor Suppressor Genes Using a Drosophila Model
With 1600 eyes, a pair of antennae, 6 legs, and an open circulatory system, the
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Clinical Implications of p53 Mutations in Lung Cancer
The p53 tumor-suppressor gene plays a crucial role in the cellular response to s
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Detection of Apoptosis in Ovarian Cells In Vitro and In Vivo Using the Annexin V-Affinity Assay
The ability of a cell to undergo apoptosis is crucial during development, tissue
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Drug Delivery Approaches for Ovarian Cancer Therapy
Tumor-specific drug delivery represents a challenging issue that restricts the c
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Current Applications of Nanotechnology for Magnetic Resonance Imaging of Apoptosis
Apoptosis, or programmed cell death, is a morphologically and biochemically dist
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Genetic Manipulation of Yeast to Identify Genes Involved in Regulation of Chemosensitivity
Fission and budding yeast have been regarded as valuable tools for studying seve
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Analysis of Cell Cycle Progression and Genomic Integrity in Early Lethal Knockouts
Owing to their importance in normal cell division, DNA damage checkpoint and rep
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Multidrug Resistance in Cancer
It is becoming increasingly clear that the proliferation of human tumours is dri
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Immunosuppressors as Multidrug Resistance Reversal Agents
Multidrug-resistance (MDR) is the major reason for failure of cancer therapy. AT
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Biochemical Analysis of the Native TRAIL Death-Inducing Signaling Complex
The extrinsic apoptosis pathway is activated when certain members of the tumor n
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Targeting Damage-Associated Molecular Pattern Molecules (DAMPs) and DAMP Receptors in Melanoma
Damage-associated molecular pattern molecules (DAMPs) are proteins released from
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Pathological Assessment of Ovarian Cancer
Ovarian neoplasms are notoriously heterogeneous-the World Health Organization cl
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Estrogen-Responsive Ovarian Cancer Xenografts
The use of human tumor xenografts grown in immunodeficient animals as a model fo
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