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Functional Analysis of the Spindle-Checkpoint Proteins Using an In Vitro Ubiquitination Assay
The spindle checkpoint helps to ensure the fidelity of chromosome segregation du
2025-03-14 45 -
Quality Assurance of Predictive Markers in Breast Cancer
It has been estimated that in 2002, 555,500 Americans will have died of cancer,
2025-03-14 43 -
Development of Rituximab-Resistant B-NHL Clones: An In Vitro Model for Studying Tumor Resistance to
Therapeutic strategies for cancer include chemotherapy, immunotherapy, and radia
2025-03-14 45 -
The Prevention and Genetics of Pancreatic Cancer: A Programmatic Approach
Pancreatic cancer (PC) is typically a fatal disease due to its rapid growth and
2025-03-14 53 -
MRD Detection in B-Cell Non-Hodgkin Lymphomas Using Ig Gene Rearrangements and Chromosomal Transloca
Minimal residual disease (MRD) diagnostics is of high clinical relevance in pati
2025-03-14 44 -
Circumventing Tumor Resistance to Chemotherapy by Nanotechnology
Patient relapse and metastasis of malignant cells is very common after standard
2025-03-14 39 -
Mechanisms of Multidrug Resistance in Cancer
The development of multidrug resistance (MDR) to chemotherapy remains a major ch
2025-03-14 39 -
Syngeneic Murine Metastasis Models: B16 Melanoma
Animal studies are costly, time consuming, and subject to several restrictive re
2025-03-14 45 -
Establishment of Primary Cultures from Ovarian Tumor Tissue and Ascites Fluid
We have refined the technique for isolating and propagating cultures of primary
2025-03-14 44 -
Tumor Markers in Screening for Ovarian Cancer
Tumor markers are used for multiple purposes in clinical care, including screeni
2025-03-14 42 -
Real-Time Polymerase Chain Reaction of Immunoglobulin Rearrangements for Quantitative Evaluation of
The evaluation of minimal residual disease (MRD) is critical in the evaluation o
2025-03-14 44 -
An In Vitro Osteoclast-Forming Assay to Measure Myeloma Cell-Derived Osteoclast-Activating Factors
Much of the morbidity and mortality associated with the plasma cell (PC) maligna
2025-03-14 44 -
Analyzing Checkpoint Controls in Human Skin
A short-term whole-skin organ culture model has been established to enable the i
2025-03-14 45 -
Role of Cytokines in Pathology of Melanoma and Use of Biologic Response Modifiers in Melanoma
Growth of normal cells is regulated by polypeptides that act via specific cellul
2025-03-14 62 -
Mapping of Tumor Suppressor Genes in Ovarian Cancers
Although cancer is fundamentally a genetic disease, in the majority of cancers t
2025-03-14 54
