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  • Implementing the Modular MHC Model for Predicting Peptide Binding

    Implementing the Modular MHC Model for Predicting Peptide Binding

    The challenge of predicting which peptide sequences bind to which major histocom

    2025-07-09 2
  • Improvement of Proteolytic Stability Through In Silico Engineering

    Improvement of Proteolytic Stability Through In Silico Engineering

    VHHs usually display high physical and proteolytic stability, but in some cases

    2025-07-09 2
  • Improvement of Single Domain Antibody Stability by Disulfide Bond Introduction

    Improvement of Single Domain Antibody Stability by Disulfide Bond Introduction

    The successful medical application of single domain antibodies largely depends o

    2025-07-09 3
  • Improving Antibody Binding Affinity and Specificity for Therapeutic Development

    Improving Antibody Binding Affinity and Specificity for Therapeutic Development

    Affinity maturation is an important part of the therapeutic antibody development

    2025-07-09 2
  • Improving Expression of scFv Fragments by Co-expression of Periplasmic Chaperones

    Improving Expression of scFv Fragments by Co-expression of Periplasmic Chaperones

    Today, recombinant protein expression in E. coli is usually considered a routine

    2025-07-09 2
  • Improving Phage Display Throughput by Using Hyperphage, Miniaturized Titration and pVIII (g8p) ELISA

    Improving Phage Display Throughput by Using Hyperphage, Miniaturized Titration and pVIII (g8p) ELISA

    Hyperphage is a substitute for M13KO7 helper phage used in antibody phage displa

    2025-07-09 2
  • Improving the Sensitivity of the ELISPOT Analyses of Antigen-Specific Cellular Immune Responses in R

    Improving the Sensitivity of the ELISPOT Analyses of Antigen-Specific Cellular Immune Responses in R

    The close similarities in hematopoietic and immune systems of humans and rhesus

    2025-07-09 2
  • In Silico De-Immunization

    In Silico De-Immunization

    This protocol shows how to reduce immunogenicity by removing CD4+ T cell epitope

    2025-07-09 2
  • In Silico Prediction of Peptide-MHC Binding Affinity Using SVRMHC

    In Silico Prediction of Peptide-MHC Binding Affinity Using SVRMHC

    The binding between peptide epitopes and major histocompatibility complex (MHC)

    2025-07-09 2
  • In Situ Detection of Epstein-Barr Virus DNA and Viral Gene Products

    In Situ Detection of Epstein-Barr Virus DNA and Viral Gene Products

    Primary Epstein-Barr virus (EBV) infection is followed by a life-long persistenc

    2025-07-09 2
  • In Situ Hybridization to Human Chromosomes of an Alkaline Phosphatase-Labeled Centromeric Probe

    In Situ Hybridization to Human Chromosomes of an Alkaline Phosphatase-Labeled Centromeric Probe

    The application of in situ hybridization and the underlying rationale are descri

    2025-07-09 2
  • In Situ RT-PCR and Hybridization Techniques

    In Situ RT-PCR and Hybridization Techniques

    In situ polymerase chain reaction (PCR) is a very powerful tool, which enhances

    2025-07-09 2
  • In SituHybridization for Cytokines in Human Tissue Biopsies

    In SituHybridization for Cytokines in Human Tissue Biopsies

    In situ hybridization (ISH) involves hybridization of labeled nucleic acid probe

    2025-07-09 2
  • In Vitro Analyses of the Immunosuppressive Properties of Neural Stem/Progenitor Cells Using Anti-CD3

    In Vitro Analyses of the Immunosuppressive Properties of Neural Stem/Progenitor Cells Using Anti-CD3

    Neural stem/progenitor cells (NSPCs) are multi-potent cells defined by their abi

    2025-07-09 2
  • In Vitro and In Vivo Analyses of Regulatory T Cell Suppression of CD8+ T Cells

    In Vitro and In Vivo Analyses of Regulatory T Cell Suppression of CD8+ T Cells

    The study of regulatory T cells (Treg) requires methods for both in vivo and in

    2025-07-09 3