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Models for Gain-of-Function and Loss-of-Function of MMPs: Transgenic and Gene Targeted Mice
The most powerful approach for studying gene function in an intact animal is to
2025-02-18 27 -
Prenatal Diagnostics on Uncultured Amniocytes
Fluorescence in situ hybridization (FISH) in prenatal diagnostics permits the de
2025-02-18 26 -
Methods for Creating Mutations in C. elegans That Extend Lifespan
The principle of commonly used methods to create mutations in the nematode Caeno
2025-02-18 18 -
Mouse Models of Viral Infection: Influenza Infection in the Lung
Respiratory viral infections are a major cause of morbidity and mortality. Prote
2025-02-18 18 -
Freezing and Thawing cells
Freezing and Thawing cellsFreezing It is best to freeze cells that are growing r
2025-02-18 17 -
Adult Cell Fate Reprogramming: Converting Liver to Pancreas
Regenerative medicine aims at producing new cells for repair or replacement of d
2025-02-18 23 -
Molecular Modeling and Molecular Dynamics Simulations of Membrane Transporter Proteins
In silico methods are increasingly being used to address problems of biological
2025-02-18 34 -
Oral and Pharyngeal Epithelial Keratinocyte Culture
Primary human oral epithelial cells are readily available and have been recently
2025-02-18 33 -
Analysis of Change
When the same subjects or laboratory animals are observed across a set of differ
2025-02-18 27 -
Immunoglobulin Class Switching: In Vitro Induction and Analysis
During an immune response, B lymphocytes can switch expression of immunoglobulin
2025-02-18 38 -
Gene Delivery to Mesenchymal Stem Cells
Successful gene therapy technology relies on the delivery of the therapeutic pro
2025-02-18 35 -
Preparation of Template DNA and Labeling Techniques
A variety of probes can be used for in situ hybridization, depending on the appl
2025-02-18 39 -
细胞遗传学(cytogenetics)
遗传学和细胞学结合建立了细胞遗传学,主要是从细胞学的角度, 特别是从染色体的结构和功能, 以及染色体和其他细胞器的关系来研究遗传现象, 阐明遗传和变异的机制。
2025-02-18 42 -
胆固醇(cholesterol)
胆固醇存在于真核细胞膜中。胆固醇分子由三部分组成: 极性的头部、非极性的类固醇环结构和一个非极性的碳氢尾部。胆固醇的分子较其他膜脂要小, 双亲媒性也较低。胆固醇
2025-02-18 30 -
Monitoring Nutrient Signaling Through the Longevity Protein p66SHC1
Nutrient availability and nutrient-dependent biochemical signals represent major
2025-02-18 38