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Improvement of Single Domain Antibody Stability by Disulfide Bond Introduction
The successful medical application of single domain antibodies largely depends o
2025-07-09 18 -
Improving Antibody Binding Affinity and Specificity for Therapeutic Development
Affinity maturation is an important part of the therapeutic antibody development
2025-07-09 14 -
Improving Expression of scFv Fragments by Co-expression of Periplasmic Chaperones
Today, recombinant protein expression in E. coli is usually considered a routine
2025-07-09 19 -
Improving Phage Display Throughput by Using Hyperphage, Miniaturized Titration and pVIII (g8p) ELISA
Hyperphage is a substitute for M13KO7 helper phage used in antibody phage displa
2025-07-09 25 -
Improving the Sensitivity of the ELISPOT Analyses of Antigen-Specific Cellular Immune Responses in R
The close similarities in hematopoietic and immune systems of humans and rhesus
2025-07-09 22 -
In Silico De-Immunization
This protocol shows how to reduce immunogenicity by removing CD4+ T cell epitope
2025-07-09 25 -
In Silico Prediction of Peptide-MHC Binding Affinity Using SVRMHC
The binding between peptide epitopes and major histocompatibility complex (MHC)
2025-07-09 22 -
In Situ Detection of Epstein-Barr Virus DNA and Viral Gene Products
Primary Epstein-Barr virus (EBV) infection is followed by a life-long persistenc
2025-07-09 18 -
In Situ Hybridization to Human Chromosomes of an Alkaline Phosphatase-Labeled Centromeric Probe
The application of in situ hybridization and the underlying rationale are descri
2025-07-09 29 -
In Situ RT-PCR and Hybridization Techniques
In situ polymerase chain reaction (PCR) is a very powerful tool, which enhances
2025-07-09 34 -
In SituHybridization for Cytokines in Human Tissue Biopsies
In situ hybridization (ISH) involves hybridization of labeled nucleic acid probe
2025-07-09 26 -
In Vitro Analyses of the Immunosuppressive Properties of Neural Stem/Progenitor Cells Using Anti-CD3
Neural stem/progenitor cells (NSPCs) are multi-potent cells defined by their abi
2025-07-09 23 -
In Vitro and In Vivo Analyses of Regulatory T Cell Suppression of CD8+ T Cells
The study of regulatory T cells (Treg) requires methods for both in vivo and in
2025-07-09 24 -
In Vitro and In Vivo Assays for High-Molecular-Weight Pegylated Muteins of Granulocyte Colony-Stimul
The hematopoietic growth factor granulocyte colony-stimulating factor (G-CSF) ha
2025-07-09 21 -
In Vitro and In Vivo Models to Study Chemokine Regulation of Angiogenesis
Angiogenesis is defined as the generation of new blood vessels from preexisting
2025-07-09 15