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  • Base-Modified Oligonucleotides With Increased Duplex Stability: Pyrazolo[3,4-d] Pyrimidines Replacin

    Base-Modified Oligonucleotides With Increased Duplex Stability: Pyrazolo[3,4-d] Pyrimidines Replacin

    Oligonucleotides incorporating 8-aza-7-dazapurines (pyrazolo[3,4-d]pyrimidines)

    2025-04-14 10
  • Hybridization of Fluorescein-Labeled Oligonucleotide Probes and Enhanced Chemiluminescence Detection

    Hybridization of Fluorescein-Labeled Oligonucleotide Probes and Enhanced Chemiluminescence Detection

    Oligonucleotide synthesizers are now commonplace with the result that oligonucle

    2025-04-14 10
  • Synthesis and Purification of Phosphorodithioate DNA

    Synthesis and Purification of Phosphorodithioate DNA

    Oligonucleotide analogs bearing modified phosphodiester linkages have been the f

    2025-04-14 13
  • Production of DNA Hybridization Probes with Digoxigenin-Modified Nucleotides by Random Hexanucleotid

    Production of DNA Hybridization Probes with Digoxigenin-Modified Nucleotides by Random Hexanucleotid

    Oligolabeling using random hexanucleotide primers (1 ) is an effective method fo

    2025-04-14 8
  • Manual Oligonucleotide Synthesis Using the Phosphoramidite Method

    Manual Oligonucleotide Synthesis Using the Phosphoramidite Method

    Oligodeoxyribonucleotides may be synthesized on a solid support, which allows fo

    2025-04-14 10
  • Multiplex Polymerase Chain Reaction

    Multiplex Polymerase Chain Reaction

    Often, studies require the polymerase chain reaction (PCR) amplification of seve

    2025-04-14 12
  • DNA Profiling: Theory and Practice

    DNA Profiling: Theory and Practice

    Of the vast range of techniques in use in modern molecular biology, DNA protilin

    2025-04-14 14
  • Cyclic Guanosine 5-Monophosphate Binding to Regulatory GAF Domains of Photoreceptor Phosphodiesteras

    Cyclic Guanosine 5-Monophosphate Binding to Regulatory GAF Domains of Photoreceptor Phosphodiesteras

    Of the 11 families of mammalian cyclic nucleotide phosphodiesterases (PDEs), 5 c

    2025-04-14 14
  • Analysis of cGMP Signaling in Adipocytes

    Analysis of cGMP Signaling in Adipocytes

    Obesity has reached pandemic dimensions with more than half a billion adults aff

    2025-04-14 11
  • Synthesis of O-Glycopeptides and Construction of Glycopeptide Microarrays

    Synthesis of O-Glycopeptides and Construction of Glycopeptide Microarrays

    O -Glycosylation of proteins is an important modification which affects biologic

    2025-04-14 12
  • Study of GPCRProtein Interactions Using Gel Overlay Assays and Glutathione-S-Transferase-Fusion Prot

    Study of GPCRProtein Interactions Using Gel Overlay Assays and Glutathione-S-Transferase-Fusion Prot

    Numerous recent studies have suggested that the predicted cytosolic domains of G

    2025-04-14 14
  • Quantification of Endogenous Retinoids

    Quantification of Endogenous Retinoids

    Numerous physiological processes require retinoids, including development, nervo

    2025-04-14 13
  • Sequential Formation of Regioselective Disulfide Bonds in Synthetic Peptides with Multiple Disulfide

    Sequential Formation of Regioselective Disulfide Bonds in Synthetic Peptides with Multiple Disulfide

    Numerous methods have been developed for the formation of disulfide bonds in rec

    2025-04-14 14
  • Measurement of eNOS and iNOS mRNA Expression Using Reverse Transcription Polymerase Chain Reaction

    Measurement of eNOS and iNOS mRNA Expression Using Reverse Transcription Polymerase Chain Reaction

    Numerous cell populations are capable of producing nitric oxide (NO) from L -arg

    2025-04-14 10
  • Photobiotin-Labeled DNA and RNA Hybridization Probes

    Photobiotin-Labeled DNA and RNA Hybridization Probes

    Nucleic acid hybridization, the formation of a duplex between two complementary

    2025-04-14 11