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A Non-covalent Peptide-Based Strategy for Ex Vivo and In Vivo Oligonucleotide Delivery
The dramatic acceleration in identification of new nucleic acid-based therapeuti
2025-03-28 25 -
Saturation-Recovery Electron Paramagnetic Resonance Discrimination by Oxygen Transport (DOT) Method
The discrimination by oxygen transport (DOT) method is a dual-probe saturation-r
2025-03-28 16 -
The Use of Restriction Endonucleases
The discovery of the mode of action of the class of bacterial enzymes known as r
2025-03-27 17 -
A screen to identify drug resistant variants to target-directed anti-cancer agents
The discovery of oncogenes and signal transduction pathways important for mitoge
2025-03-27 32 -
In Vitro Selection of Metal Ion-Selective DNAzymes
The discovery of DNAzymes that can catalyze a wide range of reactions in the pre
2025-03-27 21 -
Photorhabdus luminescens luxCDABE Promoter Probe Vectors
The discovery and characterizatton of c&acting promoter regions and transacting
2025-03-27 27 -
Preparation of Direct, Enzyme-Labeled DNA Probes
The direct labeling of nucleic acid probes with horseradish peroxidase (HRP) was
2025-03-27 19 -
Preparation of Horseradish Peroxidase-Labeled Probes
The direct labeling of nucleic acid probes with horseradish peroxidase (HRP) was
2025-03-27 30 -
Synthesis of (2R, 3R, 4R, 5S)-5-tert-Butyloxycarbonylamino-3,4-Dihydroxy-2-1sopropyl-3,4-O,O-Isoprop
The dipeptidic dihydroxyethylene isostere (27, 3R , 4R , 5S )-5-tert -butyloxy-c
2025-03-27 20 -
Sequencing DNA Fragments Cloned into M13 and Phagemid Vectors
The dideoxy chain-termination method (1 ) involves enzymatic elongation of a oli
2025-03-27 22 -
Amino Acid Profiling for the Diagnosis of Inborn Errors of Metabolism
The diagnosis of inherited metabolic disorders of amino acid (AA) metabolism is
2025-03-27 18 -
Purification of Synthetic Oligonucleotides by Preparative Gel Electrophoresis
The development of the chemistry for solid-phase oligonucleotide synthesis has e
2025-03-27 19 -
Chiral Separation Principles: An Introduction
The development of methods for chiral separation on an analytical as well as on
2025-03-27 14 -
Generation of PDE4 Knockout Mice by Gene Targeting
The development of gene-targeting techniques has ushered in a new era in mouse g
2025-03-27 19 -
Automated Liquid-Liquid Extraction and Ion-Exchange Solid-Phase Extraction for Initial Purification
The development of combinatorial chemistry has made a profound impact on the pha
2025-03-27 19
