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  • Probing the Mechanics of the Complete DNA Transcription Cycle in Real-Time Using Optical Tweezers

    Probing the Mechanics of the Complete DNA Transcription Cycle in Real-Time Using Optical Tweezers

    RNA polymerase (RNAP) is a DNA-dependent motor protein that links ribonucleotide

    2025-03-27 43
  • A rapid and sensitive assay for quantification of siRNA efficiency and specificity

    A rapid and sensitive assay for quantification of siRNA efficiency and specificity

    RNA Interference has rapidly emerged as an efficient procedure for knocking down

    2025-03-27 63
  • Quantification of siRNAs In Vitro and In Vivo

    Quantification of siRNAs In Vitro and In Vivo

    RNA interference (RNAi) is a regulatory mechanism of eukaryotic cells that uses

    2025-03-27 49
  • Nonradioactive Methods for the Detection of RNA-Protein Interaction

    Nonradioactive Methods for the Detection of RNA-Protein Interaction

    RNA in biological systems is associated with proteins. Recent work in eukaryotes

    2025-03-27 44
  • Preparation of RNA Gel Blots

    Preparation of RNA Gel Blots

    RNA gel blots (often referred to as Northern gel blots) are frequently used in t

    2025-03-27 35
  • Preparation of RNA Dot Blots

    Preparation of RNA Dot Blots

    RNA dot hybridizations were first described by Kafatos et al. (1 ). These hybrid

    2025-03-27 29
  • Quantitation of Ribozyme Target Abundance by QCPCR

    Quantitation of Ribozyme Target Abundance by QCPCR

    Ribozymes show promise as therapeutic agents for the downregulation of specific

    2025-03-27 36
  • Computer-Aided Calculation of the Local Folding Potential of Target RNA and Its Use for Ribozyme Des

    Computer-Aided Calculation of the Local Folding Potential of Target RNA and Its Use for Ribozyme Des

    Ribozymes first bind their target via complementary sequences like a conventiona

    2025-03-27 48
  • Maxizyme Technology

    Maxizyme Technology

    Ribozymes are small and versatile nucleic acids that can cleave RNAs at specific

    2025-03-27 54
  • Ligation of RNA Molecules by the Hairpin Ribozyme

    Ligation of RNA Molecules by the Hairpin Ribozyme

    Ribozymes are capable of catalyzing a variety of RNA cleavage, ligation, and spl

    2025-03-27 49
  • Crystallographic Analysis of Small Ribozymes and Riboswitches

    Crystallographic Analysis of Small Ribozymes and Riboswitches

    Ribozymes and riboswitches are RNA motifs that accelerate biological reactions a

    2025-03-27 44
  • Ribozyme as an approach for growth suppression of human pancreatic cancer

    Ribozyme as an approach for growth suppression of human pancreatic cancer

    Ribozymes (catalytic RNAs, RNA enzymes) are effective modulators of gene express

    2025-03-27 54
  • Assay for Evaluating Ribonuclease H-Mediated Degradation of RNA-Antisense Oligonucleotide Duplexes

    Assay for Evaluating Ribonuclease H-Mediated Degradation of RNA-Antisense Oligonucleotide Duplexes

    Ribonucleases H are complex enzymes whose functions are not clearly understood,

    2025-03-27 37
  • Analysis of the Role of RhoGDI1 and Isoprenylation in the Degradation of RhoGTPases

    Analysis of the Role of RhoGDI1 and Isoprenylation in the Degradation of RhoGTPases

    RhoGDI1 is one of the three major regulators of the Rho switch along with RhoGEF

    2025-03-27 95
  • Analysis of Rho GTPase Activation in Saccharomyces cerevisiae

    Analysis of Rho GTPase Activation in Saccharomyces cerevisiae

    Rho proteins act as molecular switches to control multiple cellular processes. T

    2025-03-27 44