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  • A screen to identify drug resistant variants to target-directed anti-cancer agents

    A screen to identify drug resistant variants to target-directed anti-cancer agents

    The discovery of oncogenes and signal transduction pathways important for mitoge

    2025-03-27 56
  • In Vitro Selection of Metal Ion-Selective DNAzymes

    In Vitro Selection of Metal Ion-Selective DNAzymes

    The discovery of DNAzymes that can catalyze a wide range of reactions in the pre

    2025-03-27 49
  • Photorhabdus luminescens luxCDABE Promoter Probe Vectors

    Photorhabdus luminescens luxCDABE Promoter Probe Vectors

    The discovery and characterizatton of c&acting promoter regions and transacting

    2025-03-27 50
  • Preparation of Direct, Enzyme-Labeled DNA Probes

    Preparation of Direct, Enzyme-Labeled DNA Probes

    The direct labeling of nucleic acid probes with horseradish peroxidase (HRP) was

    2025-03-27 48
  • Preparation of Horseradish Peroxidase-Labeled Probes

    Preparation of Horseradish Peroxidase-Labeled Probes

    The direct labeling of nucleic acid probes with horseradish peroxidase (HRP) was

    2025-03-27 71
  • Synthesis of (2R, 3R, 4R, 5S)-5-tert-Butyloxycarbonylamino-3,4-Dihydroxy-2-1sopropyl-3,4-O,O-Isoprop

    Synthesis of (2R, 3R, 4R, 5S)-5-tert-Butyloxycarbonylamino-3,4-Dihydroxy-2-1sopropyl-3,4-O,O-Isoprop

    The dipeptidic dihydroxyethylene isostere (27, 3R , 4R , 5S )-5-tert -butyloxy-c

    2025-03-27 49
  • Sequencing DNA Fragments Cloned into M13 and Phagemid Vectors

    Sequencing DNA Fragments Cloned into M13 and Phagemid Vectors

    The dideoxy chain-termination method (1 ) involves enzymatic elongation of a oli

    2025-03-27 42
  • Amino Acid Profiling for the Diagnosis of Inborn Errors of Metabolism

    Amino Acid Profiling for the Diagnosis of Inborn Errors of Metabolism

    The diagnosis of inherited metabolic disorders of amino acid (AA) metabolism is

    2025-03-27 45
  • Purification of Synthetic Oligonucleotides by Preparative Gel Electrophoresis

    Purification of Synthetic Oligonucleotides by Preparative Gel Electrophoresis

    The development of the chemistry for solid-phase oligonucleotide synthesis has e

    2025-03-27 37
  • Chiral Separation Principles: An Introduction

    Chiral Separation Principles: An Introduction

    The development of methods for chiral separation on an analytical as well as on

    2025-03-27 36
  • Generation of PDE4 Knockout Mice by Gene Targeting

    Generation of PDE4 Knockout Mice by Gene Targeting

    The development of gene-targeting techniques has ushered in a new era in mouse g

    2025-03-27 36
  • Automated Liquid-Liquid Extraction and Ion-Exchange Solid-Phase Extraction for Initial Purification

    Automated Liquid-Liquid Extraction and Ion-Exchange Solid-Phase Extraction for Initial Purification

    The development of combinatorial chemistry has made a profound impact on the pha

    2025-03-27 50
  • In Vivo ChIP for the Analysis of Microdissected Tissue Samples

    In Vivo ChIP for the Analysis of Microdissected Tissue Samples

    The development of chromatin immunoprecipitation assays (ChIP) as a tool to exam

    2025-03-27 52
  • In Vivo Screening of Ligand-Dependent Hammerhead Ribozymes

    In Vivo Screening of Ligand-Dependent Hammerhead Ribozymes

    The development of artificial switches of gene expression is of high importance

    2025-03-27 39
  • Using the Flp-In T-Rex System to Regulate GPCR Expression

    Using the Flp-In T-Rex System to Regulate GPCR Expression

    The development of a cell-based system that allows the integration of a gene of

    2025-03-27 42