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Multiple Labeling Techniques for Fluorescence Microscopy
As described in Chapter 2 by Brooks, it has long been possible to localize antig
2025-03-19 23 -
On-Demand Cleavable Linkers for Radioimmunotherapy
Radioimmunotherapy (RIT) using radiolabeled antibodies or its fragments holds gr
2025-03-19 31 -
Intratumoral Gene Transfer of the Cytosine Deaminase Gene for the Treatment of Breast Cancer
One of the major limitations of conventional cancer chemotherapy is its lack of
2025-03-19 32 -
Screening for miRNA Expression Changes Using Quantitative PCR (Q-PCR)
In this section, we describe the use of Applied Biosystems TaqMan Array microRNA
2025-03-19 41 -
Genetic Epidemiology Studies in Hereditary Non-Polyposis Colorectal Cancer
Genetic epidemiology studies in hereditary non-polyposis colorectal cancer (HNPC
2025-03-19 29 -
Detection of Telomerase Enzyme Activity by TRAP Assay
The telomeric repeat amplification protocol (TRAP) assay, first published by Kim
2025-03-19 38 -
Ex Vivo Cytokine Gene Transfer in Melanomas by Using Particle Bombardment
Melanoma is a malignant tumor of neuroectodermal origin with an increasing incid
2025-03-19 28 -
YKL-40: A Novel Marker Shared by Chronic Inflammation and Oncogenic Transformation
YKL-40, a member of ‘mammalian chitinase-like proteins’, is secreted by macropha
2025-03-19 29 -
Fluorescence In Situ Hybridization (FISH) to Metaphase and Interphase Chromosomes
The unambiguous identification of human chromosomes became possible with the dis
2025-03-19 23 -
In Situ Hybridization of Cells and Tissue Sections
In situ hybridization (ISH) has become a powerful and versatile method for the d
2025-03-19 28 -
TUNEL and Immunofluorescence Double-Labeling Assay for Apoptotic Cells with Specific Antigen(s)
A double-labeling assay for detecting apoptotic cells, using the terminal deoxyn
2025-03-19 39 -
Molecular Cytogenetic Applications in Analysis of the Cancer Genome
Cancer cells exhibit nonrandom and complex chromosome abnormalities. The role of
2025-03-19 30 -
Analysis of the TLR/NF-B Pathway in Antigen-Presenting Cells in Malignancies Promoted by Inflammatio
Activation of the transcription factor, nuclear factor of κB (NF-κB), has recent
2025-03-19 26 -
Conversion Technology and Cancer Predispositions
The field of diagnostics has gathered the first crop of the genetic insurgency i
2025-03-19 18 -
PARP Cleavage and Caspase Activity to Assess Chemosensitivity
The ultimate aim of cancer therapeutics is to eradicate tumor cells. Upon lethal
2025-03-19 17
