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Methods for Analysis of Brain Tumor Stem Cell and Neural Stem Cell Self-Renewal
Neural stem cells (NSC) self-renew and are multipotent, producing neurons and gl
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Interaction Between the Retinoblastoma Protein and Protein Phosphatase 1 During the Cell Cycle
The functions of the retinoblastoma protein (pRb) are in part regulated by rever
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Correlation of Caspase Activity and In Vitro Chemo-Response in Epithelial Ovarian Cancer Cell Lines
The immediate assessment of response to therapy is most beneficial to ovarian ca
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Measuring DNA Adducts by Immunoassay (ELISA)
A large proportion of anti-cancer drugs act by causing chemical modifications to
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Detection of Telomerase Activity in Patients with Pancreatic Cancer
Telomerase, which ensures the unlimited proliferation by adding TTAGGG repeat at
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Cancer Occurrence
In this chapter, we describe the variability of cancer occurrence by using measu
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COLD-PCR Enriches Low-Level Variant DNA Sequences and Increases the Sensitivity of Genetic Testing
Detection of low-level mutations is important for cancer biomarker and therapy t
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SAGE as a Strategy to Isolate Cancer-Related Genes
Serial Analysis of Gene Expression (SAGE) is a sequence-based approach that enab
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Models of Hormone Resistance In Vitro and In Vivo
Estrogen receptor (ER)-positive MCF-7 breast cancer cell lines can be used both
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Evaluation of Environmental and Personal Susceptibility Characteristics That Modify Genetic Risks
Study design in understanding gene—environment interaction plays a crucial role.
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Angiogenesis Assays
Angiogenesis—the formation of a vascular network—is essential for the support of
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Antisense Oligonucleotides as Research Tools
The use of antisense oligonucleotides as both research tools and therapeutic mol
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Fluorescence In Situ Hybridization Assessment of c-myc Gene Amplification in Breast Tumor Tissues
This chapter details methods used for analysis of DNA copy-number changes in bre
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Apoptosis: A Technical Overview
Physiological or programmed cell death plays an important role during a variety
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Cloning Differentially Expressed Genes Using Rapid Subtraction Hybridization (RaSH)
Differential gene expression represents the entry point for comprehending comple
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