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Comparative Multiplex PCR and Allele-Specific Expression Analysis in Human Lung Cancer: Tools to Fac
When lung cancer is detected, in the majority of cases it cannot be effectively
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Tumor Deprivation of Oxygen and Tumor Suppressor Gene Function
Tumor hypoxia originates from the inability of neovasculature to provide an adeq
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Antisense Oligonucleotides Targeting RI Subunit of Protein Kinase A: In Vitro and In Vivo Anti-Tumor
cAMP-dependent protein kinase (PKA) is involved in various cellular functions su
2025-03-19 25 -
Proteomic Profiling of Ovarian Cancer Models Using TMT-LC-MS/MS
Herein, we have utilized two cellular models of epithelial ovarian cancer (EOC),
2025-03-19 18 -
Immunohistochemical Detection of Ornithine Decarboxylase as a Measure of Chemosensitivity Testing
The development of reliable methods for the in vitro testing of sensitivity of c
2025-03-19 26 -
9 Intracellular Single-Chain Antibodies for Gene Therapy
The delineation of the molecular basis of cancer in general, allows for the poss
2025-03-19 23 -
Multiple Labeling Techniques for Fluorescence Microscopy
As described in Chapter 2 by Brooks, it has long been possible to localize antig
2025-03-19 23 -
On-Demand Cleavable Linkers for Radioimmunotherapy
Radioimmunotherapy (RIT) using radiolabeled antibodies or its fragments holds gr
2025-03-19 32 -
Intratumoral Gene Transfer of the Cytosine Deaminase Gene for the Treatment of Breast Cancer
One of the major limitations of conventional cancer chemotherapy is its lack of
2025-03-19 32 -
Screening for miRNA Expression Changes Using Quantitative PCR (Q-PCR)
In this section, we describe the use of Applied Biosystems TaqMan Array microRNA
2025-03-19 42 -
Genetic Epidemiology Studies in Hereditary Non-Polyposis Colorectal Cancer
Genetic epidemiology studies in hereditary non-polyposis colorectal cancer (HNPC
2025-03-19 29 -
Detection of Telomerase Enzyme Activity by TRAP Assay
The telomeric repeat amplification protocol (TRAP) assay, first published by Kim
2025-03-19 38 -
Ex Vivo Cytokine Gene Transfer in Melanomas by Using Particle Bombardment
Melanoma is a malignant tumor of neuroectodermal origin with an increasing incid
2025-03-19 28 -
YKL-40: A Novel Marker Shared by Chronic Inflammation and Oncogenic Transformation
YKL-40, a member of ‘mammalian chitinase-like proteins’, is secreted by macropha
2025-03-19 30 -
Fluorescence In Situ Hybridization (FISH) to Metaphase and Interphase Chromosomes
The unambiguous identification of human chromosomes became possible with the dis
2025-03-19 23
