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Induction of Tumor Cell Apoptosis by TRAIL Gene Therapy
Members of the tumor necrosis factor (TNF) superfamily influence a variety of im
2025-03-17 21 -
Topoisomerase I and II Activity Assays
DNA topoisomerases I and II (top1 and top2, respectively) are ubiquitous enzymes
2025-03-17 24 -
Fluorescence itIn Situ Hybridization
In situ hybridization describes the annealing of a labeled nucleic acid to compl
2025-03-17 21 -
Microsatellite Analysis to Assess Chromosome 18q Status in Colorectal Cancer
Loss of the long arm of chromosome 18 (18q) is one of the most common genetic ch
2025-03-17 18 -
Mitochondria Potential, Bax Activation, and Programmed Cell Death
Since the discovery of the key role of cytochrome C in the activation of caspase
2025-03-17 15 -
Investigating Macrophage and Malignant Cell Interactions In Vitro
Within most human and murine cancers there is an abundant macrophage population,
2025-03-17 26 -
Identification of Protein Interaction Partners by the Yeast Two-Hybrid System
The two-hybrid system is a genetic method to search for and to identify direct i
2025-03-17 18 -
Immunity of Lentiviral Vector-Modified Dendritic Cells
Innovative approaches to induce a strong immune response are key to the success
2025-03-17 23 -
Cell Cycle and Drug Sensitivity
Induction of tumor cell death by chemotherapeutic modalities often occurs in a c
2025-03-17 21 -
Development of Orthotopic Pancreatic Tumor Mouse Models
Genetically engineered mouse models of pancreatic cancer that recapitulate human
2025-03-17 20 -
Analysis of Cell Cycle by Flow Cytometry
Described are four widely used procedures to analyze the cell cycle by flow cyto
2025-03-17 23 -
Fluorescence In Situ Hybridization for BCR-ABL
The BCR-ABL fusion gene arises as a result of a reciprocal translocation between
2025-03-17 35 -
Measurement of Ceramide and Sphingolipid Metabolism in Tumors: Potential Modulation of Chemotherapy
Ceramide is a bioactive lipid involved in the induction of apoptosis and is the
2025-03-17 21 -
Isolation of Tumor Suppressor Genes in Melanoma by cDNA Microarray
The multistep genetic alterations thought to involve both oncogenes and tumor su
2025-03-17 32 -
The Oncofetal Protein p65 in Breast Cancer Detection
It has been known for some time that steroid and thyroid hormones can regulate c
2025-03-17 20
