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The Guideline of the Design and Validation of MiRNA Mimics
The miRNA mimic technology (miR-Mimic) is an innovative approach for gene silenc
2025-03-18 28 -
Optical Proteolytic Beacons for In Vivo Detection of Matrix Metalloproteinase Activity
The exuberant expression of proteinases by tumor cells has long been associated
2025-03-18 26 -
In Vivo Vascular Leakage Assay
This chapter describes the methods for measuring the increase in vascular permea
2025-03-18 23 -
The Identification of Colon Cancer Susceptibility Genes by Using Genome-Wide Scans
Recent studies have indicated that in ∼35% of all colorectal cancer (CRC) cases,
2025-03-18 13 -
Immunocompetent Mouse Model of Ovarian Cancer for In Vivo Imaging
Syngeneic and transgenic mouse models are important tools for the study of the b
2025-03-18 18 -
Stability and Ubiquitination of the Tumor Suppressor Protein p53
The ubiquitin-dependent proteolysis pathway constitutes a major pathway in the c
2025-03-18 16 -
The Clinical Use of PET/CT in the Evaluation of Melanoma
Positron emission tomography combined with computed tomography (PET/CT) has emer
2025-03-18 18 -
Adhesion of Tumor Cells to Matrices and Endothelium
Cell adhesion is a process fundamental to tumor metastasis. Egress of cells from
2025-03-18 23 -
Representational Difference Analysis of Gene Expression
The technique of representational difference analysis (RDA) allows the selective
2025-03-18 20 -
Signal Transduction Study Using Gene-Targeted Embryonic Stem Cells
Gene targeting is one of the most powerful tools to define the role of signaling
2025-03-18 25 -
Characterization of Nonmalignant and Malignant Prostatic Stem/Progenitor Cells by Hoechst Side Popul
Recent technical progress in the field of cancer stem/progenitor cell research r
2025-03-18 21 -
Designing Plasmid Vectors
Nonviral gene therapy vectors are commonly based on recombinant bacterial plasmi
2025-03-18 18 -
Immunohistochemistry and In Situ Hybridization in Pancreatic Neoplasia
There are many types of pancreatic neoplasms. Pathologic examination, which incl
2025-03-18 23 -
Identification of Senescence in Cancer Cells
Senescence is thought to be a programmed response to protect cells from DNA dama
2025-03-18 16 -
Cell Aggregation Assays
Invasion of carcinoma cells is the result of a disequilibrium between invasion p
2025-03-18 18
