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  • Identification of Tumor-Associated Antigens as Diagnostic and Predictive Biomarkers in Cancer

    Identification of Tumor-Associated Antigens as Diagnostic and Predictive Biomarkers in Cancer

    Many studies demonstrated that cancer sera contain antibodies which react with a

    2025-03-18 39
  • Detection of Low Levels of DNA Fragmentation in Ovarian Tumor Cell Lines

    Detection of Low Levels of DNA Fragmentation in Ovarian Tumor Cell Lines

    The techniques presented in this chapter describe the experimental procedure for

    2025-03-18 32
  • Polymerase Chain Reaction Based Methods for Assessing Chimerism Following Allogeneic Bone Marrow Tra

    Polymerase Chain Reaction Based Methods for Assessing Chimerism Following Allogeneic Bone Marrow Tra

    It is important to be able to assess the contribution of donor cells to the graf

    2025-03-18 31
  • Genetic Modification of Cell Lines to Enhance Their Metastatic Capability

    Genetic Modification of Cell Lines to Enhance Their Metastatic Capability

    Metastasis is the final step in tumor progression from a benign cell to a fully

    2025-03-18 35
  • Tumor Necrosis Factor as a Pharmacological Target

    Tumor Necrosis Factor as a Pharmacological Target

    Tumor necrosis factor (TNF) was originally described as a molecule with antitumo

    2025-03-18 26
  • Practical Methods for Tissue Microarray Construction

    Practical Methods for Tissue Microarray Construction

    The tissue microarray (TMA) of Kononen et al. is an extension of an idea origina

    2025-03-18 32
  • Quantitative, Competitive RT-PCR Analysis of Biomarkers in the Study of Neoplasia

    Quantitative, Competitive RT-PCR Analysis of Biomarkers in the Study of Neoplasia

    The current status of the evaluation of many neoplasias (e.g., carcinoma of the

    2025-03-18 133
  • Detection of Chromosomal Aberrations in Lung Tissue and Peripheral Blood Lymphocytes Using Interphas

    Detection of Chromosomal Aberrations in Lung Tissue and Peripheral Blood Lymphocytes Using Interphas

    Many cancers arise from gene-environment interactions, where susceptible individ

    2025-03-18 30
  • Tumor-Targeted Salmonella: Strain Development and Expression of the HSV-tK Effector Gene

    Tumor-Targeted Salmonella: Strain Development and Expression of the HSV-tK Effector Gene

    Gene therapy approaches to cancer treatment have been limited by the ability of

    2025-03-18 28
  • Use of Diphenylamine in the Detection of Apoptosis

    Use of Diphenylamine in the Detection of Apoptosis

    The diphenylamine assay is a very useful tool in measuring apoptosis by determin

    2025-03-18 38
  • Diagnosis and Monitoring of AML1-MTG8 (ETO)-Positive Acute Myeloid Leukemia by Qualitative and Real-

    Diagnosis and Monitoring of AML1-MTG8 (ETO)-Positive Acute Myeloid Leukemia by Qualitative and Real-

    Assessing the level of residual disease in leukemia is vital for evaluating pati

    2025-03-18 30
  • Isolation and Culture of Renal Cancer Cell Lines

    Isolation and Culture of Renal Cancer Cell Lines

    Renal cell carcinoma (RCC) represents approximately 2% of all cancers and accoun

    2025-03-18 23
  • Prognostic Relevance of Angiogenic, Proliferative, and Apoptotic Factors in Lung Carcinomas: A Case

    Prognostic Relevance of Angiogenic, Proliferative, and Apoptotic Factors in Lung Carcinomas: A Case

    Angiogenesis—the development and formation of new blood vessels—is important in

    2025-03-18 20
  • Immunohistochemical Diagnostic and Prognostic Markers for Melanoma

    Immunohistochemical Diagnostic and Prognostic Markers for Melanoma

    Recent studies in our laboratory have identified novel molecular diagnostic and

    2025-03-18 25
  • Transfection and DNA-Mediated Gene Transfer

    Transfection and DNA-Mediated Gene Transfer

    The advent of recent technologies such as gene expression microarrays and high-t

    2025-03-18 32