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The EGFR Pathway as an Example for Genotype: Phenotype Correlation in Tumor Genes
Tumor-specific and germ-line variations of DNA significantly contribute to tumor
2025-03-15 20 -
Transfection Assays for Transformation of Model Colonic Cell Lines
The recognition of cancer as a genetic disease has changed the approach investig
2025-03-15 22 -
Solving Problems in Multiplex FISH
Over the last 15 yr, advances in molecular biology have allowed improvements in
2025-03-15 28 -
Marker Utility for Combination Therapy
Melanoma is a heterogeneous disease for which monotherapies are likely to fail i
2025-03-15 30 -
Compartmentalized Protein Kinase C Activation in Ovarian Carcinoma Cells
Protein kinase C (PKC), a family of phospholipid-dependent serine/threonine kina
2025-03-15 21 -
Overexpression of PRV-1 Gene in Polycythemia Rubra Vera and Essential Thrombocythemia
The polycythemia rubra vera 1 gene (PRV-1 ), a member of the urokinase-type plas
2025-03-15 19 -
Molecular Diagnosis of Acute Myeloid Leukemia with Maturation, FAB-Type M2
Nonrandom chromosome abnormalities frequently are seen in particular subtypes of
2025-03-15 19 -
Neurosphere Culture and Human Organotypic Model to Evaluate Brain Tumor Stem Cells
The brain tumor stem cell (BTSC) hypothesis is based on the premise that there i
2025-03-15 18 -
Matrix Metalloproteinases and Their Inhibitors
Matrix metalloproteinases (MMPs) are a group of 16 enzymes that are capable of d
2025-03-15 19 -
Laser Microdissection Sample Preparation for RNA Analyses
Gene expression analysis provides an insight into the unique and defining biomol
2025-03-15 20 -
Functional Analysis of the Antimitogenic Activity of Tumor Suppressors
Loss of tumor suppressors contributes to numerous cancer types. Many, but not al
2025-03-15 23 -
NanoparticleAptamer Conjugates for Cancer Cell Targeting and Detection
Aptamers are DNA or RNA oligonucleotide sequences that selectively bind to their
2025-03-15 20 -
Gene Expression Profile Analysis of Lymphomas
Through the genome-wide characterization of a cell type’s transcriptome, gene ex
2025-03-15 17 -
Quantitative, Fluorescence-Based In-Situ Assessment of Protein Expression
As companion diagnostics grow in prevalence and importance, the need for accurat
2025-03-15 22 -
Detection of TNF and TNF Receptor mRNA in Cells and Tissues
We describe a semiquantitative reverse transcriptase polymerase chain reaction (
2025-03-15 24
