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  • Developing Anti-HER2/neu Single-Chain Fv Fragments from Phage Display Libraries

    Developing Anti-HER2/neu Single-Chain Fv Fragments from Phage Display Libraries

    One of the major failures of conventional cancer therapy has been the inability

    2025-03-15 29
  • Cytogenetic Analysis and Reporting

    Cytogenetic Analysis and Reporting

    Use of appropriate methods to produce analysable metaphase spreads and high-qual

    2025-03-15 18
  • Array-Based Comparative Genomic Hybridization as a Tool for Analyzing the Leukemia Genome

    Array-Based Comparative Genomic Hybridization as a Tool for Analyzing the Leukemia Genome

    Comparative genomic hybridization (CGH) is arguably the most significant technic

    2025-03-15 20
  • Methylation Analysis of CpG Islands

    Methylation Analysis of CpG Islands

    The application of Southern blotting to determine the methylation status of a pa

    2025-03-15 20
  • Chromatin Immunoprecipitation Assays: Molecular Analysis of Chromatin Modification and Gene Regulati

    Chromatin Immunoprecipitation Assays: Molecular Analysis of Chromatin Modification and Gene Regulati

    Gene expression pattern in cancer cells differ significantly from their normal c

    2025-03-15 21
  • Analysis of Transplanted Bone Marrow-Derived Cells in Chronic Pancreatitis

    Analysis of Transplanted Bone Marrow-Derived Cells in Chronic Pancreatitis

    Pancreatic cancer is a uniformly lethal disease characterized by a strong stroma

    2025-03-15 25
  • Isolation of a Purified Epithelial Cell Population from Human Colon

    Isolation of a Purified Epithelial Cell Population from Human Colon

    While in situ techniques have been valuable in identifying the presence and loca

    2025-03-15 18
  • Inflammatory Response of Tumor-Activated Hepatic Sinusoidal Endothelium as a Target for the Screenin

    Inflammatory Response of Tumor-Activated Hepatic Sinusoidal Endothelium as a Target for the Screenin

    The pathogenesis of cancer dissemination and metastasis involves a cascade of in

    2025-03-15 19
  • Analyzing Markers of Apoptosis In Vitro

    Analyzing Markers of Apoptosis In Vitro

    Cell death by apoptosis was first identified based on morphological changes repr

    2025-03-15 20
  • Measuring Gene Expression from Cell Cultures by Quantitative Reverse-Transcriptase Polymerase Chain

    Measuring Gene Expression from Cell Cultures by Quantitative Reverse-Transcriptase Polymerase Chain

    Quantitative reverse transcriptase polymerase chain reaction (qRT-PCR) offers a

    2025-03-15 18
  • Quantitative Angiogenesis in Breast Cancer

    Quantitative Angiogenesis in Breast Cancer

    Over the last few years, great advances in our understanding in tumor neovascula

    2025-03-15 22
  • FISH Techniques

    FISH Techniques

    The impression is sometimes given that fluorescence in situ hybridization (FISH)

    2025-03-15 20
  • Genetic Suppressor Elements in the Characterization and Identification of Tumor Suppressor Genes

    Genetic Suppressor Elements in the Characterization and Identification of Tumor Suppressor Genes

    The subject of the present chapter is the genetic suppressor element (GSE) metho

    2025-03-15 24
  • Direction of the Recognition Specificity of Cytotoxic T Cells Toward Tumor Cells by Transduced, Chim

    Direction of the Recognition Specificity of Cytotoxic T Cells Toward Tumor Cells by Transduced, Chim

    Cellular transformation does not necessarily require the expression of proteins

    2025-03-15 19
  • Transactivation and Transrepression Studies with p53

    Transactivation and Transrepression Studies with p53

    The methods outlined in this chapter are designed to facilitate the study of the

    2025-03-15 23