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Development of Bacterial Vectors for Tumor-Targeted Gene Therapy
Gene therapy holds great promise for the treatment of cancer. The success of the
2025-03-15 23 -
Analysis of EMT by Flow Cytometry and Immunohistochemistry
Ovarian cancer stem cells (OCSCs) are in a transitional phase between epithelial
2025-03-15 23 -
Prediction of the Biological Effect of Polymorphisms Within MicroRNA Binding Sites
MicroRNAs (miRNAs) are negative gene regulators acting at the 3′UTR level, modul
2025-03-15 21 -
Comparative Genomic Hybridization
Comparative genomic hybridization (CGH ) allows a genome-wide survey of the rela
2025-03-15 18 -
Breast Cancer Proteomics Using Two-Dimensional Electrophoresis: Studying the Breast Cancer Proteome
Proteomics has emerged as a powerful approach for studying disease-associated ch
2025-03-15 33 -
PCR Microsatellite Analysis of LOH in Ovarian Tumors
The “two-hit” theory of tumor suppressor gene (TSG) inactivation predicts that l
2025-03-15 31 -
The EGFR Pathway as an Example for Genotype: Phenotype Correlation in Tumor Genes
Tumor-specific and germ-line variations of DNA significantly contribute to tumor
2025-03-15 20 -
Transfection Assays for Transformation of Model Colonic Cell Lines
The recognition of cancer as a genetic disease has changed the approach investig
2025-03-15 22 -
Solving Problems in Multiplex FISH
Over the last 15 yr, advances in molecular biology have allowed improvements in
2025-03-15 28 -
Marker Utility for Combination Therapy
Melanoma is a heterogeneous disease for which monotherapies are likely to fail i
2025-03-15 30 -
Compartmentalized Protein Kinase C Activation in Ovarian Carcinoma Cells
Protein kinase C (PKC), a family of phospholipid-dependent serine/threonine kina
2025-03-15 21 -
Overexpression of PRV-1 Gene in Polycythemia Rubra Vera and Essential Thrombocythemia
The polycythemia rubra vera 1 gene (PRV-1 ), a member of the urokinase-type plas
2025-03-15 19 -
Molecular Diagnosis of Acute Myeloid Leukemia with Maturation, FAB-Type M2
Nonrandom chromosome abnormalities frequently are seen in particular subtypes of
2025-03-15 19 -
Neurosphere Culture and Human Organotypic Model to Evaluate Brain Tumor Stem Cells
The brain tumor stem cell (BTSC) hypothesis is based on the premise that there i
2025-03-15 18 -
Matrix Metalloproteinases and Their Inhibitors
Matrix metalloproteinases (MMPs) are a group of 16 enzymes that are capable of d
2025-03-15 19
