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Immunohistochemical Assays of Farnesyltransferase Inhibition in Patient Samples
As a result of early reports indicating that farnesylation was required for matu
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AIDS-Associated Pulmonary Cancers
Neoplastic disease occurs more frequently in immunocompromised patients than in
2025-03-14 23 -
Laser-Capture Microdissection
Laser-capture microdissection is a recently discovered state-of-the-art method t
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Production and Characterization of Receptor-Specific TNF Muteins
Tumor necrosis factor (TNF) is a pleiotropic cytokine with a wide range of biolo
2025-03-14 24 -
Functional Analysis of the Spindle-Checkpoint Proteins Using an In Vitro Ubiquitination Assay
The spindle checkpoint helps to ensure the fidelity of chromosome segregation du
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Quality Assurance of Predictive Markers in Breast Cancer
It has been estimated that in 2002, 555,500 Americans will have died of cancer,
2025-03-14 22 -
Development of Rituximab-Resistant B-NHL Clones: An In Vitro Model for Studying Tumor Resistance to
Therapeutic strategies for cancer include chemotherapy, immunotherapy, and radia
2025-03-14 23 -
The Prevention and Genetics of Pancreatic Cancer: A Programmatic Approach
Pancreatic cancer (PC) is typically a fatal disease due to its rapid growth and
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MRD Detection in B-Cell Non-Hodgkin Lymphomas Using Ig Gene Rearrangements and Chromosomal Transloca
Minimal residual disease (MRD) diagnostics is of high clinical relevance in pati
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Circumventing Tumor Resistance to Chemotherapy by Nanotechnology
Patient relapse and metastasis of malignant cells is very common after standard
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Mechanisms of Multidrug Resistance in Cancer
The development of multidrug resistance (MDR) to chemotherapy remains a major ch
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Syngeneic Murine Metastasis Models: B16 Melanoma
Animal studies are costly, time consuming, and subject to several restrictive re
2025-03-14 24 -
Establishment of Primary Cultures from Ovarian Tumor Tissue and Ascites Fluid
We have refined the technique for isolating and propagating cultures of primary
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Tumor Markers in Screening for Ovarian Cancer
Tumor markers are used for multiple purposes in clinical care, including screeni
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Real-Time Polymerase Chain Reaction of Immunoglobulin Rearrangements for Quantitative Evaluation of
The evaluation of minimal residual disease (MRD) is critical in the evaluation o
2025-03-14 21