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A High-Throughput Methodology for Identifying Molecular Targets Overexpressed in Lung Cancers
As discussed in previous chapters, lung cancer is one of most deadly diseases an
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Assessment of Insulin-Like Growth Factors and Mutagen Sensitivity as Predictors of Lung Cancer Risk
Insulin-like growth factors (IGFs) are mitogenic peptide hormones involved in th
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Some Difficult Choices in Cytogenetics
It is rare for a full-fledged malignancy cytogenetics service to be started as a
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Analysis of the Potential for Pancreatic Cancer Metastasis In Vitro and In Vivo
Pancreatic cancer remains a challenging disease, with an overall 5-year survival
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Animal Models of Endotoxic Shock
Endotoxin/lipopolysaccharide (LPS) is the major mediator that triggers the cellu
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Coculture of Prostate Cancer Cells
The progression of prostate cancer is accompanied by the breakdown of normal epi
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Multiple Myeloma: Challenges and Opportunities
Multiple myeloma (MM) is a B-cell neoplasm in which malignant plasma cells accum
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Construction and Characterization of RNase-Based Targeted Therapeutics
Cell targeting agents such as antibodies, antibody fragments (sFvs), or growth f
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The Effects of Butyrate and the Role of c-myc in N.1 Ovarian Carcinoma Cells Determined by Northern
Two hypothetical concepts are discussed as means to cure cancer: 1) extinction o
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RNase Protection Assay Analysis of mRNA for TGF1-3 in Ovarian Tumors
RNase protection assays provide a level of sensitivity some 20-50-fold greater t
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Serum and Tissue Biomarkers in the Prognosis and Treatment of Breast Cancer
Several nuclear and membrane proteins are emerging as important markers of breas
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The rapid progress in understanding the molecular biology of cancer cells has made a large impact on
Phosphorodiamidate morpholino oligomers (PMO), which have a neutral chemistry, a
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Recombinant Single-Chain and Disulfide-Stabilized Fv Immunotoxins for Cancer Therapy
The rapid progress in understanding the molecular biology of cancer cells has ma
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Bioactive Interleukin-6 Levels in Serum and Ascites as a Prognostic Factor in Patients with Epitheli
Interleukin-6 (IL-6) is a multifunctional cytokine displaying diverse biologic f
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Basic Principles for the Study of Metastasis Using Animal Models
Metastasis is the most devastating aspect of cancer, and the major reason for tr