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Assays for HSP90 and Inhibitors
The molecular chaperone HSP90 is currently under investigation as a promising ta
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Regulatory Aspects for Translating Gene Therapy Research into the Clinic
Gene therapy products are highly regulated, therefore moving a promising candida
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99mTc-Annexin A5 Uptake and Imaging to Monitor Chemosensitivity
Most anticancer agents act by inducing apoptosis in sensitive tumor cells. Hence
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Microsatellite Analysis of the Insulin-Like Growth Factor II Receptor in Colorectal Carcinomas
The insulin-like growth factor II (IGFII) growth control pathway is comprised of
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Frozen Biopsy Collection and Storage: Frozen Biopsy Samples
This chapter describes some simple standard operating procedures for the regular
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Chromosomal Copy Number Analysis in Melanoma Diagnostics
The majority of melanocytic neoplasms can be correctly diagnosed using routine h
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Rocking Adhesion Assay System to Study Adhesion and Transendothelial Migration of Cancer Cells
Adhesion of metastatic cancer cells to the vascular endothelium of the target or
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DNA Methylation Changes in Prostate Cancer
Epigenetic alterations contribute significantly to the development and progressi
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Detection of MicroRNAs in Cultured Cells and Paraffin-Embedded Tissue Specimens by In Situ Hybridiza
Determination of gene expression is essential for understanding the role of a gi
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2-DE-Based Proteomics for the Analysis of Metastasis-Associated Proteins
Two-dimensional electrophoresis (2-DE) is a high-resolution technique for analys
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Targeting the Mitochondria to Enhance Tumor Suppression
A continuous supply of biochemical energy is required in order for cells to perf
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High-Throughput Technology: Green Fluorescent Protein to Monitor Cell Death
Reliable assessment of cell death is now pivotal to many research programs aimin
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A High-Throughput Methodology for Identifying Molecular Targets Overexpressed in Lung Cancers
As discussed in previous chapters, lung cancer is one of most deadly diseases an
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Assessment of Insulin-Like Growth Factors and Mutagen Sensitivity as Predictors of Lung Cancer Risk
Insulin-like growth factors (IGFs) are mitogenic peptide hormones involved in th
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Some Difficult Choices in Cytogenetics
It is rare for a full-fledged malignancy cytogenetics service to be started as a
