Clot Retraction
The study of clot retraction in vitro has been adopted as a simple and reproduci
The study of clot retraction in vitro has been adopted as a simple and reproducible approach to assess platelet function. Plasma clots should retract away from the sides of a glass tube within a few hours allowing the rapid characterization of outside-in signaling through platelet integrin αIIb β3 . In this chapter, we describe the role of platelets in fibrin clot retraction and provide a detailed description of the methods used to assess this process.
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Effector Recruitment Method to Study Spatially Regulated Activation of Ras and Rho GTPases
Ras and Rho family GTPases control a wide variety of cellula...
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Binding Affinity and Kinetic Analysis of Nuclear Receptor/Co-Regulator Interactions Using Surface Pl
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