Lyophilization of Nonviral Gene Delivery Systems
This chapter presents a qualitative description of the freeze-drying process as
This chapter presents a qualitative description of the freeze-drying process as it pertains to the development of stable, dry polycation-DNA complex formulations. It is not intended to be a comprehensive treatise on freeze-drying. Readers are referred to a series of excellent papers by Pikal (1 –5 ) for more detailed, quantitative explanations of the freeze-drying process.