Cytogenetics of Solid Tumours
The study of chromosome abnormalities in solid tumours provides valuable information for the diagnosis and prognostic stratification of a variety of tumour subtypes. Technical challenges are encountered in tissue culture, harvesting and finally the interpretation of complex chromosome abnormalities. Molecular cytogenetic studies complement karyotype analysis, but the ability to assess all chromosome abnormalities simultaneously underscores the value of conventional cytogenetic analysis. This chapter provides detailed methods for solid tumour cytogenetics from tissue culture to banding.
- 上一篇
Experimental Models and Methods in Antibody Targeting of Renal Cell Carcinoma
Metastatic renal cell carcinoma (RCC) is incurable and there...
- 下一篇
Reconstruction of Geno-Phenotypic Evolutionary Sequences from Intracellular Patterns of Molecular Ab
In this chapter we describe an approach to the analysis of h...