Login
欢迎浏览恩派尔生物资料网
我要投稿 请登录 免费注册 安全退出

您现在的位置是: 首页 > 实验方法 > 细胞技术

细胞技术

Detection of Circulating Tumor Cells by Photoacoustic Flowmetry

2025-03-15 细胞技术 加入收藏
Detection of circulating tumor cells (CTCs) in human blood and lymph systems has

Detection of circulating tumor cells (CTCs) in human blood and lymph systems has the potential to aid clinical decision making in the treatment of cancer (Cristofanilli et al. New Engl J Med 351:781–791, 2004; Check Cap Today 19:1.76–1.86, 2005; Braun and Naume J Clin Oncol 8:1623–1626, 2005). The presence of CTCs may signify the onset of metastasis, indicate relapse, or may be used to monitor disease progression. We built and tested a photoacoustic flowmetry system for detecting circulating melanoma cells (CMCs) by exploiting the broadband absorption spectrum of melanin within CMCs. The device was tested on cultured melanoma cells in saline suspension, melanoma cells spiked in human blood, and in a Stage IV melanoma patient. The device showed a detection threshold of a single pigmented melanoma cell from culture. Results show the potential to assay blood samples from healthy and metastatic patients for the presence of cancerous melanoma providing a method for cancer screening.

文章底部广告位

文章评论

加载中~