The Characterization of Chromosomal Abnormalities Using Fluorescence In SituHybridization Procedures
Cytogenetic changes are important in understanding the pathogenesis of disease.
Cytogenetic changes are important in understanding the pathogenesis of disease. Karyotypic analysis is particularly useful when investigatmg conditions such as human malignancies, where aneuploidy and structural chromosome rearrangements are commonly found, as in the human leukemias. In these, karyotypes can show a wide range of different structural rearrangements, with highly specific chromosome abnormalities that are used in the classification of leukemras (1 ), which, in turn, are related to specific clinical features.
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Sequential Fluorescence In Situ Hybridization Analysis for Trisomy 12 in B-Cell Chronic Lymphocytic
Tumor-specific chromosomal abnormalities are attracting a la...
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Silicon Nanowire Biosensor for Ultrasensitive and Label-Free Direct Detection of miRNAs
MicroRNA (miRNA), a large and growing class of 18–24-nucleot...