Determination of Artemisinin in Artemisia annua L. by Off-Line Supercritical Fluid Extraction and Su

Malaria is a major disease in many countries and, according to an estimation by the World Health Organization (WHO), approx 300–500 million people contract malaria yearly and almost 2 million die annually (1 ). Controlling malaria is now becoming very problematic because of the developing resistance of Plasmodium falciparum to chloroquine, mefloquine, and other commonly used antimalarial drugs.