DISEASE AND CAUSES | PATHOPHYSIOLOGY | SIGNS AND SYMPTOMS |
Kaposi's sarcoma |
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| A malignant cancer arising from vascular endothelial cells, Kaposi's sarcoma affects endothelial tissue, which compromises all blood vessels. | - Red-purple circular lesions, slightly raised on the face, arms, neck, and legs
- Internal lesions, especially in GI tract, identified by biopsy
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Keratitis |
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- Inflammation of cornea due to microorganisms, trauma, or autoimmune disorders
| Bacterial infection leads to ulceration of the cornea. | - Decreased visual acuity
- Pain
- Photophobia
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Kidney cancer |
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- Renal cell carcinoma associated with obesity and cigarette smoking
| Tumors of various cell types and patterns that are usually aggressive in growth and affect younger patients. | - Hematuria
- Flank pain
- Palpable mass
- Weight loss
- Anemia
- Fever
- Hypertension
- Increased erythrocyte sedimentation rate
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Klinefelter syndrome |
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- Genetic abnormality, affecting males resulting from an extra X chromosome
| Seminiferous tubule dysgenesis. | - At puberty, testicles fail to mature
- Degenerative testicular changes
- Infertility
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Kyphosis |
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- An excessive curvature of the spine with convexity backward due to a congenital anomaly, tuberculosis, syphilis, malignant or compression fracture, arthritis, or rickets
| Pathophysiology is related to causative factor. | - Abnormally rounded thoracic curve
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