A Brief Introduction to RNAi and MicroRNAs in Stem Cells
Recently, RNAi, including microRNAs (miRNAs), has become an important tool to in
Recently, RNAi, including microRNAs (miRNAs), has become an important tool to investigate the regulatory mechanism of stem cell maintenance and differentiation. In this short chapter, we will give a brief overview of the discovery history, functions, and mechanisms of RNAi and miRNAs. We will also discuss RNAi as a tool to study stem cell function and the potential future practical applications.
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Microscopic Computed Tomography-Based Skeletal Phenotyping for Genetic Model Organisms
Forward and reverse genetics now enable researchers to under...
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Chromosomal Double-Strand Breaks Introduced in Mammalian Cells by Expression of I-Sce I Endonuclease
Until recently, investigators interested in analyzing the re...