Production of Recombinant Human IgG Antibodies in the Baculovirus Expression System

Despite antibody fragments like scFv or Fab are sufficient for various tasks, complete recombinant IgG is sometimes needed. Production of IgG molecules is not generally achievable in E. coli . Insect cells are able to produce IgG and the use of the Baculovirus systems allows a rapid cloning and production timeline. The following protocol describes a Baculovirus Expression System for the Production of Recombinant Human IgG Antibodies.