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Dissecting the Urokinase Activation Pathway Using Urokinase-Activated Anthrax Toxin
Anthrax toxin is a three-part toxin secreted by Bacillus anthracis , consisting
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Comparative Genomic Hybridization Analysis
Molecular genetic investigations of human tumors have increased our understandin
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Gene Therapy Vectors Harboring AFP Regulatory Sequences: Preparation of an Adenoviral Vector
A goal of cancer research is to develop therapies that can selectively kill tumo
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Bcl-2 Family Immunohistochemistry
In recent years, immunohistochemistry as applied to the Bcl-2 family of proteins
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Comparative Genomic Hybridization Technique
Screening for chromosomal changes in solid tumors was long hindered by methodolo
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Novel Effective Tumor Vaccines for Hepatocellular Carcinoma
Hepatocellular carcinoma (HCC) is one of the most frequent malignancies in numer
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Genome-Wide DNA Methylation Profiling: The mDIP-Chip Technology
Aberrant DNA methylation is one of the major characteristics of tumor cells in a
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Hybrid Capture of Putative Tumor Suppressor Genes
During the last part of the twentieth century, research on human cancer increasi
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Zoom-In Array Comparative Genomic Hybridization (aCGH) to Detect Germline Rearrangements in Cancer S
Disease predisposing germline mutations in cancer susceptibility genes may consi
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Analysis of the Spindle-Assembly Checkpoint in HeLa Cells
The spindle-assembly checkpoint involves signaling at kinetochores, which leads
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Assessing Matrix Metalloproteinase Expression and Activity in Hepatocellular Carcinomas
The matrix metalloproteinases (MMPs) constitute a large family of zincand calciu
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Glycoproteomic Analysis by Two-Dimensional Electrophoresis
Changes in N-linked glycosylation are known to occur during the development of c
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Application of Recombinant Antibodies in Cancer Patients
As a consequence of the invention of the hybridoma technology by K�hler and Mils
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Fluorescence In Situ Hybridization for Cancer-Related Studies
Cytogenetic analysis of tumour material has been greatly enhanced over the past
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Immunocytochemical Detection and Characterisation of Individual Micrometastatic Tumour Cells
Detection of micrometastases in the bone marrow (BM) of cancer patients may be a
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