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aking Sense of DNA Microarray Data
The fast advance of genomic science and nucleic acid detection technology provid
2025-03-17 57 -
Determination of Biological Parameters on Fine-Needle Aspirates from Non-Small Cell Lung Cancer
Non-small cell lung cancer (NSCLC) accounts for approximately 75% of all human l
2025-03-17 66 -
LDI-PCR: Identification of Known and Unknown Gene Fusions of the Human MLL Gene
The human MLL gene is one of the most promiscuous recombination hot spots of our
2025-03-17 72 -
Pharmacogenomics
Pharmacogenomics encompasses several major areas including the identification an
2025-03-17 59 -
Protein Tyrosine Kinase and Phosphatase Expression Profiling in Human Cancers
Alterations of protein tyrosine kinase and tyrosine phosphatase are often associ
2025-03-17 67 -
Single-Nucleotide Polymorphism (SNP) Analysis to Associate Cancer Risk
Identification of hereditary factors that predispose to cancer allows targeted c
2025-03-17 56 -
Pharmacokinetic and Pharmacodynamic Implications of P-Glycoprotein Modulation
Modulation of P-glycoprotein (Pgp)-mediated transport has significant pharmacoki
2025-03-17 49 -
CHK1 Kinase Activity Assay
Mammalian CHK1 is a Ser/Thr effector kinase that plays critical roles in the DNA
2025-03-17 52 -
Epidemiology of Brain Tumors
Gliomas account for more than 70% of all brain tumors, and of these, glioblastom
2025-03-17 58 -
TUNEL Assay as a Measure of Chemotherapy-Induced Apoptosis
Chemotherapy induces injury to tumor cells, which subsequently die by a number o
2025-03-17 55 -
Molecular Analysis of Genetic Instability Caused by Chronic Inflammation
Genetic instability is a hallmark of human cancers. It is the driving force for
2025-03-17 56 -
Inhibiting Proinflammatory NF-B Signaling Using Cell-Penetrating NEMO Binding Domain Peptides
Nuclear factor kappa B (NF-κB) is an inducible transcription factor that regulat
2025-03-17 61 -
Assessment of Gelatinases (MMP-2 and MMP-9 by Gelatin Zymography
The invasion and metastasis of tumor cells has been shown to require proteolytic
2025-03-17 63 -
Detection of t(2;5)(p23;q35)Translocation by Long-Range PCR of Genomic DNA
Many types of human leukemias and lymphomas are associated with specific chromos
2025-03-17 75 -
The Use of Matrigel to Facilitate the Establishment of Human Cancer Cell Lines as Xenografts
Matrigel is a solubilized tissue basement membrane matrix rich in extracellular
2025-03-17 107