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Use of siRNA to Study the Function of MDC1 in DNA Damage Responses
Small interfering RNA (siRNA) technology has emerged as a powerful genetic tool
2025-03-15 59 -
Complete Array of HOX Gene Expression by RQ-PCR
In mammals the HOX network consists of 39 genes which encode master regulators o
2025-03-15 69 -
Production of Plasmid DNA as a Pharmaceutical
Developments in gene therapy, cell therapy, and DNA vaccination require a pharma
2025-03-15 57 -
Functional Analysis of Tumor Suppressor Genes in Mice
The utilization of mice as a model for human cancer goes back to the generation
2025-03-15 47 -
Microarray-Based Comparative Genomic Hybridization (Array-CGH) as a Useful Tool for Identifying Gene
Alterations in the genome that lead to changes in DNA sequence copy number are a
2025-03-15 45 -
Immunoscope Analysis of T-Lymphocytes Infiltrating Melanocytic Tumors
Melanomas are most frequently infiltrated by actively proliferating T-lymphocyte
2025-03-15 32 -
The Chick Embryo Metastasis Model
The growth and dissemination of malignant tumors continues to have a devastating
2025-03-15 35 -
The Regulation of Tumor Suppressor Genes by Oncogenes
Tumor suppressor genes (TSGs) and oncogenes represent the ying and the yang of c
2025-03-15 40 -
Cancer Gene Profiling in Prostate Cancer
Gene profiling and expression analysis using microarrays have made a significant
2025-03-15 35 -
Detection and Analysis of DNA Methylation by Pyrosequencing
Pyrosequencing is a “sequencing by synthesis” technique which can be used to qua
2025-03-15 50 -
Non-RI Protocols for L-myc Allelotyping and Deletion Mapping of Chromosome 1p in Primary Lung Cancer
Deletion at a specific locus in a chromosome in cancer cells is assumed to imply
2025-03-15 50 -
Cyclooxygenase Inhibitors Induce Colon Cancer Cell Apoptosis Via PPAR 14-3-3 Pathway
Non-steroidal anti-inflammatory drugs (NSAIDs) and selective cyclooxygenase-2 (C
2025-03-15 47 -
Apoptosis Assessment by the DNA Diffusion Assay
A simple, sensitive, and reliable DNA diffusion assay for quantification of apop
2025-03-15 51 -
Epigenetic Targets in Cancer Epidemiology
Recently, it has been shown that epigenetic changes are involved in early stages
2025-03-15 48 -
Molecular and Genetic Aspects of Lung Cancer
Lung cancer is the leading cause of cancer death among men and women in the Unit
2025-03-15 39