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Generation and Characterization of p53 Mutant Mice
p53 is one of the most well-characterized members of the tumor suppressor gene f
2025-03-15 40 -
G1 and S-Phase Checkpoints, Chromosome Instability, and Cancer
Mitogen-dependent progression through the first gap phase (G1) of the mammalian
2025-03-15 37 -
Flow Cytometric Measurement of Cell Proliferation
The simplest guide to cell proliferation that can be obtained by the use of flow
2025-03-15 35 -
Incomplete DJH Rearrangements
Analysis of Ig genes in B-cell malignancies has become an essential method in mo
2025-03-15 30 -
The Impact of Hepatitis B Virus (HBV) and Hepatitis C Virus (HCV): From Research to Clinical Practic
Hepatic carcinogenesis is a complex process that involves profound alterations o
2025-03-15 38 -
Identifying Obstacles to Viral Gene Therapy for Lung Cancer: Malignant Pleural Effusions as a Paradi
We have been investigating intrapleural malignancy as a “proof of concept” clini
2025-03-15 38 -
18 Direct Sequencing for Cowden Syndrome Gene PTEN (MMAC1) Mutations
Cowden syndrome is a rare dominantly inherited condition with predisposition to
2025-03-15 42 -
UroVysion Multiprobe FISH in Urinary Cytology
Urinary cytology is used in combination with cystoscopy for the diagnosis of pri
2025-03-15 44 -
The Polymerase Chain Reaction
The polymerase chain reaction (PCR) has had a significant impact on all aspects
2025-03-15 40 -
Analyzing the G2/M Checkpoint
The G2 checkpoint prevents cells from entering mitosis when DNA is damaged, prov
2025-03-15 37 -
Mutation of p53 Tumor Suppressor Gene in Hepatocellular Carcinoma
In recent years, the most commonly observed genetic alteration in hepatocellular
2025-03-15 39 -
Identifying Genes Related to Chemosensitivity Using Support Vector Machine
In an effort to identify genes involved in chemosensitivity and to evaluate the
2025-03-15 39 -
Approaches to Proteomic Analysis of Human Tumors
The involvement of tumor suppressor genes (TSG) in cancer initiation and progres
2025-03-15 48 -
Quantitative DNA Methylation Profiling on a High-Density Oligonucleotide Microarray
Recently, the analysis and functional elucidation of CpG island methylation has
2025-03-15 38 -
One-Dimensional Genome Scanning-Detection of Genomic Changes in Ovarian Carcinoma
Genomic changes are a frequent underlying event in many malignancies, including
2025-03-15 44