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Monoclonal Antibodies: Generation and Clinical Use
Originally, the term “antibody” referred to an unknown entity in serum, which ha
2025-03-14 65 -
Adenovirus-Mediated Drug-Sensitivity Gene Therapy for Hepatocellular Carcinoma
Selective gene therapy represents a potent approach in cancer treatment that uti
2025-03-14 53 -
Understanding Metastasis Through Integrin Expression
Integrins form a major family of heterodimeric cell surface receptors. Individua
2025-03-14 52 -
Circulating Tumor Cells as Prognostic Biomarkers in Cutaneous Melanoma Patients
Detection of circulating tumor cells (CTC) in peripheral blood has been investig
2025-03-14 53 -
Fluorescence In Situ Hybridization to Chromosomes
Development of the technique of in situ hybridization (ISH) propelled the merger
2025-03-14 44 -
Alterations in the Expression of Insulin-Like Growth Factors and Their Binding Proteins in Lung Canc
The insulin-like growth factors (IGF), named for their structural homology to pr
2025-03-14 58 -
Identification of Pancreatic Cancer-Specific Cell-Surface Markers for Development of Targeting Ligan
Pancreatic cancer is generally detected at later stages with a poor prognosis an
2025-03-14 58 -
Application of Phage Display to Discovery of Tumor-Specific Homing Peptides: Developing Strategies f
Selective delivery of drugs or imaging dyes to tumor is the central challenge fo
2025-03-14 47 -
Identification of Malignant Plasma Cells by mRNA In Situ Hybridization
Patients with multiple myeloma have a clonal proliferation of malignant plasma c
2025-03-14 42 -
Pharmacogenetics of ATP-Binding Cassette Transporters and Clinical Implications
Drug resistance is a severe limitation of chemotherapy of various malignancies.
2025-03-14 42 -
Mutational Analysis of Oncogenes and Tumor Suppressor Genes in Human Cancer Using Denaturing Gradien
Denaturing gradient gel electrophoresis (DGGE) was introduced 20 years ago (1 )
2025-03-14 41 -
Promoter Methylation in Head and Neck Tumorigenesis
In addition to genetic alterations of gains and losses, epigenetic events of pro
2025-03-14 38 -
Microarray Approaches for Analysis of Tumor Suppressor Gene Function
Many tumor suppressor genes are known to function at least in part through regul
2025-03-14 38 -
Impact of Breast Cancer Resistance Protein on Cancer Treatment Outcomes
Breast cancer resistance protein (BCRP/ABCG2) was discovered in multidrug resist
2025-03-14 41 -
Characterization and Authentication of Cancer Cell Lines: An Overview
Studies of the same cell lines by different laboratories are common in the liter
2025-03-14 56