-
Polymerase Chain Reaction for Detection of the t(14;18) Translocation in Lymphomas
The t(14;18) (q21;q32) translocation was originally identified as occurring in f
2025-03-14 37 -
Peptide YY Mediates Inhibition of Tumor Growth and Inflammation
Peptide YY (PYY) orchestrates the functions of the gut and the pancreas by regul
2025-03-14 36 -
Melanoma Susceptibility Genes and Risk Assessment
Familial melanoma accounts for approximately a tenth of all melanoma cases. The
2025-03-14 29 -
Modulation of Apoptosis to Reverse Chemoresistance
Interference with the innate apoptotic activity is a hallmark of neoplastic tran
2025-03-14 31 -
Detection of Small Cell Lung Cancer by RT-PCR for Neuropeptides, Neuropeptide Receptors, or a Splice
Small cell lung cancer (SCLC) comprises a significant fraction of all lung cance
2025-03-14 40 -
Pituitary Adenoma Stem Cells
The identification of a subpopulation of brain tumor cells with potent tumorigen
2025-03-14 36 -
A Hepatitis C Virus Xenograft Mouse Efficacy Model
The lack of a robust small-animal model for hepatitis C virus (HCV) has hindered
2025-03-14 43 -
Acute Lymphoblastic Leukaemia
Cytogenetics plays an important role in the diagnosis of acute lymphoblastic leu
2025-03-14 41 -
Spectral Karyotyping in Cancer Cytogenetics
Cancer is a genetic disease. Gene mutations are not only responsible for rare he
2025-03-14 40 -
Instrumentation, Accuracy, and Quality Control Issues in Development of Quantitative Fluorescence-Im
Many fundamental questions of biology reduce to a common technical problem, how
2025-03-14 37 -
Fluorescence In Situ Hybridization (FISH) as a Tool for the Detection of Significant Chromosomal Abn
Cytogenetics is integral to the diagnosis of childhood leukaemia, particularly i
2025-03-14 37 -
Feeder Layers: Co-culture with Nonneoplastic Cells
Maintenance of a mitotically inactive feeder layer which is able to provide extr
2025-03-14 31 -
Evolution of Cytogenetic Methods in the Study of Cancer
Cytogenetic methods have not changed greatly over the last 50 years since Nowell
2025-03-14 31 -
Oncolytic Viral Therapy Using Reovirus
Current mainstays in cancer treatment such as chemotherapy, radiation therapy, h
2025-03-14 33 -
The Mammalian Two-Hybrid Assay for Detection of Coactivator-Nuclear Receptor Interactions
The two-hybrid assay was described in 1989 as a method to determine protein-prot
2025-03-14 33