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Microarray-Based CGH in Cancer
The detection of chromosome imbalances in malignancies has been a popular and us
2025-03-17 20 -
Large Scale Production of Recombinant Antibodies by Utilizing Cellulose-Binding Domains
Many recombinant proteins, particularly proteins with diagnostic and therapeutic
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Methodologies in Assaying Prostate Cancer Stem Cells
The cancer stem cell (CSC) theory posits that only a small population of tumor c
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In Vitro Invasion Assays
Epithelial ovarian cancer cells spread by two major pathways. One is by exfoliat
2025-03-17 21 -
Dissecting the Urokinase Activation Pathway Using Urokinase-Activated Anthrax Toxin
Anthrax toxin is a three-part toxin secreted by Bacillus anthracis , consisting
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Comparative Genomic Hybridization Analysis
Molecular genetic investigations of human tumors have increased our understandin
2025-03-17 21 -
Gene Therapy Vectors Harboring AFP Regulatory Sequences: Preparation of an Adenoviral Vector
A goal of cancer research is to develop therapies that can selectively kill tumo
2025-03-17 25 -
Bcl-2 Family Immunohistochemistry
In recent years, immunohistochemistry as applied to the Bcl-2 family of proteins
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Comparative Genomic Hybridization Technique
Screening for chromosomal changes in solid tumors was long hindered by methodolo
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Novel Effective Tumor Vaccines for Hepatocellular Carcinoma
Hepatocellular carcinoma (HCC) is one of the most frequent malignancies in numer
2025-03-17 23 -
Genome-Wide DNA Methylation Profiling: The mDIP-Chip Technology
Aberrant DNA methylation is one of the major characteristics of tumor cells in a
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Hybrid Capture of Putative Tumor Suppressor Genes
During the last part of the twentieth century, research on human cancer increasi
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Zoom-In Array Comparative Genomic Hybridization (aCGH) to Detect Germline Rearrangements in Cancer S
Disease predisposing germline mutations in cancer susceptibility genes may consi
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Analysis of the Spindle-Assembly Checkpoint in HeLa Cells
The spindle-assembly checkpoint involves signaling at kinetochores, which leads
2025-03-17 23 -
Assessing Matrix Metalloproteinase Expression and Activity in Hepatocellular Carcinomas
The matrix metalloproteinases (MMPs) constitute a large family of zincand calciu
2025-03-17 27
