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Emerging Clinical Issues in Melanoma in the Molecularly Targeted Era
The standard of care of patients with malignant melanoma is dramatically changin
2025-03-13 22 -
Primary Explant Cultures of Adult and Embryonic Pancreas
The developmental plasticity of adult pancreas is evidenced by the ability to un
2025-03-13 28 -
Regulation of NF-B by Oncoproteins and Tumor Suppressor Proteins
The transcription factor nuclear factor-κB (NF-κB) has been demonstrated to cont
2025-03-13 21 -
Localization of Cyclooxygenase-2 Protein Expression in Lung Cancer Specimens by Immunohistochemical
Cyclooxygenase-2 (COX-2) inhibitors comprise a group of compounds that show prom
2025-03-13 24 -
MTT Growth Assays in Ovarian Cancer
The MTT (3-[4,5-dimethylthiazol-2yl]-2,5-diphenyl tetrazolium bromide) growth as
2025-03-13 25 -
Apoptosis Detection by DNA Analysis
Apoptosis is a series of controlled sequential events resulting in cell death. T
2025-03-13 31 -
Xenopus Cell-Free Extracts to Study the DNA Damage Response
Cell-free systems derived from Xenopus eggs represent a powerful tool, intermedi
2025-03-13 30 -
Anchorage-Independent Growth of Prostate Cancer Stem Cells
Prostate cancer is a major health concern in the Western world. Prostate cancer
2025-03-13 18 -
Mutation Detection in Colorectal Cancers: Direct Sequencing of DNA Mismatch Repair Genes
The detection of unknown mutations has proved complex and time consuming, and th
2025-03-13 29 -
Gene Expression Microarrays
New methods have been developed for determining and monitoring gene expression l
2025-03-13 21 -
Detection of Apoptosis in Renal Cell Carcinoma
Apoptosis is a selective process of programmed cell death that plays an importan
2025-03-13 23 -
I1307K Mutation Detection by Allele-Specific PCR in Familial Colorectal Cancer
Familial colorectal cancer (FCC) is a hereditary form of colorectal cancer that
2025-03-13 34 -
Reciprocal Subtraction Differential RNA Display (RSDD): An Efficient Technology for Cloning Differen
Identification of differentially expressed genes is an essential step in compreh
2025-03-13 30 -
Invasion and Motility Assays
A key feature of malignant cells is their capacity to invade surrounding tissue
2025-03-13 22 -
Pathological Evaluation of Axillary Sentinel Lymph Nodes in Breast Cancer
Nodal staging is the most important prognostic factor in the management of patie
2025-03-13 22