-
HER2 FISH in Breast Cancer
The assessment of HER2/c-erbB-2/neu (hereafter HER2 ) gene amplification and pro
-
Myeloperoxidase Promoter Region Polymorphism and Lung Cancer Risk
Globally, lung cancer is the leading cause of cancer death accounting for nearly
-
7 In Vitro Methods for Evaluation of P450-Based Anticancer Gene Therapy
Cytochrome P450 genes encode drug-metabolizing enzymes that bioactivate a number
-
Targeted Alpha Therapy of Prostate Cancer
Prostate cancer (PC) is now the second most common cause of death from cancer in
-
Binding Assay for Selectins
Selectins form a group of C-type lectins, which bind to carbohydrates in a calci
-
Analysis of Alterations in a Base-Excision Repair Gene in Lung Cancer
Cellular DNA is continuously exposed to a variety of insults induced by differen
-
The SCID-hu Myeloma Model
The severe combined immune deficient human (SCID-hu) myeloma model is the only a
-
Cyclooxygenase 2-Dependent Regulation of Antitumor Immunity in Lung Cancer
Lung cancer is the leading cause of cancer death in the United States (1 ). Many
-
Markers of Tumor Burden: An Overview
Since ancient times, cancer has been known to humankind. The ancient Greeks and
-
17 Direct Sequencing for Peutz-Jeghers Gene LKB1 (STK11) Mutations
While Peutz-Jeghers syndrome (PJS) has been acknowledged as a clinical entity fo
-
Characterization of Signalling Pathways by Reverse Phase Protein Arrays
Reverse phase protein array (RPPA) is a very suitable technique to analyze large
-
Targets in Apoptosis Signaling: Promise of Selective Anticancer Therapy
The human body is composed of approximately 1014 cells, each of which is capable
-
Approaches for Monitoring Signal Transduction Changes in Normal and Cancer Cells
This chapter will describe methods to assess the activities of protein kinases.
-
Analysis of the Mouse Placenta as a Hematopoietic Stem Cell Niche
Hematopoietic stem cells are at the foundation of the blood system. Their study
-
MicroRNA Regulation of Growth Factor Receptor Signaling in Human Cancer Cells
Aberrant expression of the epidermal growth factor receptor (EGFR) and/or human
